Personalities

Natalia V. Yunusova

Natalia V. Yunusova, MD, PhD, DSc, Principal Investigator, Department of Tumor Biochemistry, Cancer Research Institute, of Tomsk NRMC.

Contact details

e-mail: bochkarevanv@oncology.tomsk.ru
tel.: +7 3622 3341

Brief Biography

After graduating from the Medical-Biological Faculty of Siberian State Medical University (Tomsk, 1994) Natalia V. Yunusova was employed at the Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences as a junior research fellow. In 1998, she received her PhD degree. After obtaining her DSc degree in 2007, she was appointed as a Principal Investigator of the Laboratory of Tumor Biochemistry, Tomsk Cancer Research Institute. Since 2014, she has been Professor at the Department of Biochemistry and Molecular Biology with the Course of Clinical Laboratory Diagnostics, Siberian State Medical University.  

Research Interests

Natalia V. Yunusova is an author of more than 150 scientific publications, including 3 books, 4 patents and 3 certificates of database registration, 2 manuals "Workshop on molecular biology" and "Workshop on medical biotechnology with the basics of molecular biology". Under her supervision, 1 thesis for DSc degree and 2 dissertations for PhD degree were defended. Her current research focuses on the study of pathogenetic aspects of malignant neoplasms associated with metabolic syndrome (endometrial and colorectal cancers) as well as the creation of algorithms used for cancer prediction. Her research interest also includes the study of the role of tetraspanins and proteases of extracellular vesicles-exosomes in the invasion and metastasis of colorectal and ovarian cancers.

Achievements, awards, and grants

Natalia V. Yunusova is a member of the Scientific Council of Cancer Research Institute of Tomsk NRMC. She is a member of the Expert Commission at the Dissertation Council, and a member of the Coordinating Commission of  Cancer Research Institute, Tomsk NRNC.

For high achievements in scientific and educational activities, Natalia V. Yunusova was awarded with the grant of the regional charity fund for the promotion of Russian medicine under the Presidium of the Russian Academy of Medical Sciences (2002-2003).  She was awarded with the Honorary Diplomas of City Administration of Tomsk for honest work and achievements in science (2008, 2012, and 2016). 

Main Publications

1. Yunusova NV, Kondakova IV, Kolomiets LA, Afanas’ev SG, Chernyshova AL, Kudryavtsev IV,  Tsydenova AA.  Molecular targets for the therapy of cancer associated with metabolic syndrome (transcription and growth factors) // Asia-Pac J Clin Oncol. -2017, 8 November;1–7. https://doi.org/10.1111/ajco.12780.

2. Yunusova N.V., Tamkovich S.N., Stakheeva M.N., Grigor’eva A.A., Somov A.K., Tugutova E.A., Kolomiets L.A., Molchanov S.V., Afanas’ev S.G., Kakurina G.V., Choinzonov E.L., Kondakova I.V.  The characterization of exosomes from biological fluids of patients with different types of cancer [Internet] // Physics of cancer: interdisciplinary problems and clinical applications. Tomsk, May 23-26, 2017 / AIP Conference Proceedings 1882, 020080; 2017. Available from: http://aip.scitation.org/doi/abs/10.1063/1.5001659.

3. Tamkovich SN, Yunusova NV, Stakheeva МN, Somov AK, Frolova АY, Kirushina NА, Afanasyev SG, Grigoryeva АE, Laktionov PP, Kondakova IV.  Isolation and characterization of exosomes from blood plasma of breast cancer and colorectal cancer patients // Biochemistry (Moscow), Suppl.Series B:  Biomedical Chemistry. 2017; 11(3):291-295.

4. Yunusova N.V., Tamkovich S.N., Stakheeva M.N., Afanas'ev S.G., Frolova A.Y., Kondakova I.V. The characterization of exosome from blood plasma of patients with colorectal cancer [Internet] // Physics of cancer: interdisciplinary problems and clinical applications. Tomsk, May 22-25, 2016 / AIP Conference Proceedings, 020070; 2016. Available from: http://aip.scitation.org/doi/abs/10.1063/1.4960289

5. Yunusova, N.V., Tamkovich, S.N., Stakheeva, M.N., Afanas'ev. S.G., Frolova, A.Y., Kondakova, I.V., “The characterization of exosome from blood plasma of patients with colorectal cancer.” AIP Conference Proceedings, 020070 (2016).

6. NataliaV Yunusova, Liudmila V Spirina, Alena E Frolova, Sergey G Afanas’ev, Elena S Kolegova, Irina V Kondakova.  Association of IGFBP-6 expression with metabolic syndrome and adiponectin and IGF-IR receptor levels in colorectal сancer // Asian P.J. of Cancer Prevention.-2016. DOI:http://dx.doi.org/10.7314/APJCP.2016.17.

7. Yunusova NV,  Villert AB,  Spirina LV, Frolova AE, Kolomiets LA,  Kondakova IV. Insulin-like growth factors and their binding proteins in tumor and ascites of ovarian cancer patients: association with response to neoadjuvant chemotherapy. Asian Pac J Cancer Prev. 2016;17(12):6215-9.

8. Spirina LV, Yunusova NV, Kondakova IV, Kolomiets LA, Koval VD, Chernyshova AL, Shpileva OV Association of growth factors, HIF-1 and NF-kB expression with proteasome in endometrial cancer  // Mol Biol Rep. 2012 Sep;39(9):8655-62. doi: 10.1007/s11033-012-1720-y.  http://www.ncbi.nlm.nih.gov/pubmed/22711307