Mikhail A. Buldakov
PhD, Senior Researcher of Laboratory of Molecular Oncology and Immunology, Cancer Research Institute, Tomsk NRMC; Head of Young Science Organization of Tomsk National Research Medical Center.
Contacts
e-mail: buldakov@oncology.tomsk.ru
tel.: +7 (3822) 28-26-86 * 3307
РИНЦ SPIN-код, 7558-4726
РИНЦ AuthorID, 135429
ResearcherID Web of Science,
Scopus (Author ID), 55932165800
ORCID 0000-0001-8276-110X
Brief CV
Work experience
2011-present: Senior Researcher, Laboratory of Molecular Oncology and Immunology, Cancer Research Institute, Tomsk NRMC
2019: Senior Researcher, Physical Electronics Department, Institute of High Current Electronics
2014-2019: Senior Researcher, Laboratory for Translational Cellular and Molecular Biomedicine, Tomsk State University
2012-2013: Member of Education, Scientific and Culture Committee of the Legislative Duma of Tomsk Region
2007-2011: Researcher, Laboratory of Immunology, Cancer Research Institute, SB RAMS
2006-2007: Junior Researcher, Laboratory of Immunology, Cancer Research Institute, SB RAMS
2003 – 2006: Technician, Laboratory of Immunology, Cancer Research Institute, SB RAMS
Education
2005-208: PhD in Physiology, Tomsk State University
2003-2005: MSc in Biology, Tomsk State University
1999-2003: BSc in Biology, Tomsk State University
Research Interests
- Radiotherapy of tumor
- Physical methods for cancer treatment
- Tumor progression and resistance
- Cell technology
Awards
- Thanks from the Council of Rectors of Tomsk Universities
- winner of the UMNIK program of the Fund for Assistance to the Development of Small Forms of Enterprises in the Scientific and Technical Field
- Laureate of the Tomsk Region Competition in the field of education, science, healthcare and culture
- winner of the Tomsk Venture Investment Fund contest “From Idea to Industrial Production” of the XIII Tomsk Innovation Forum
- winner of the Projects competition in the framework of the Investment Session “From Idea to Industrial Production” of the XIII Tomsk Innovation Forum
- diploma of the Ministry of Education of the Russian Federation
Internship
2006, 2007, 2011, 2013: Department of Radiation Research, Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan
2014, 2015: Department of Cellular and Molecular Biology of Innate Immunity Medical Faculty Mannheim, Heidelberg University
Main Publications
Author of more than 40 publications
1. Semen Goreninskii, Nadezhda Danilenko, Evgeniy Bolbasov, Anastasia Evtina, Mikhail Buldakov, Nadezhda Cherdyntseva, Muhammad Saqib, Natalia Beshchasna, Joerg Opitz, Victor Filimonov, Sergei Tverdokhlebov Enhanced properties of poly(ε-caprolactone)/polyvinylpyrrolidone electrospun scaffolds fabricated using 1,1,1,3,3,3-hexafluoro-2-propanol // Journal of Applied Polymer Science, V.138, Issue 23, p. 1-11, https://doi.org/10.1002/app.50535
2. Mitrofanova (Larionova I.), L. Tengfei, M. Zavyalova, N. Litviakov, M. Buldakov, N. Cherdyntseva, J. Kzhyshkowska. YKL-39 induces monocytes migration and angiogenesis and inversely correlates with metastasis in patients with breast cancer. Annals of Oncology. -2017. – V. 28, №. 5.
3. I. Mitrofanova, M. Zavyalova, M. Buldako, N. Cherdyntseva, J. Kzhyshkowska. Effect of neoadjuvant chemotherapy on correlation of tumor-associated macrophages with angiogenesis and lymphangiogenesis in human breast cancer. Annals of Oncology. -2017. – V. 28, №. 5.
4. Liu T, Larionova I, Litviakov N, Riabov V, Zavyalova M, Tsyganov M, Buldakov M, Song B, Moganti K, Kazantseva P, Slonimskaya E, Kremmer E, Flatley A, Klüter H, Cherdyntseva N, Kzhyshkowska J Tumor-associated macrophages in human breast cancer produce new monocyte attracting and pro-angiogenic factor YKL-39 indicative for increased metastasis after neoadjuvant chemotherapy. // Oncoimmunology. 2018 Mar 13;7(6):e1436922. doi: 10.1080/2162402X.2018.1436922.
5. Denisov E.V, Skryabin N.A, Gerashchenko T.S, Tashireva L.A, Wilhelm J, Buldakov M.A, Sleptcov A.A, Lebedev I.N, Vtorushin S.V, Zavyalova M.V, Cherdyntseva N.V, Perelmuter V.M Clinically relevant morphological structures in breast cancer represent transcriptionally distinct tumor cell populations with varied degrees of epithelial-mesenchymal transition and CD44+CD24- stemness // Oncotarget. 2017 May 19;8(37):61163-61180. doi: 10.18632/oncotarget.18022
6. Mitrofanova I., Zavyalova M., Telegina N., Buldakov M., Riabov V., Cherdyntseva N., Kzhyshkowska J. Tumor-associated macrophages in human breast cancer parenchyma negatively correlate with lymphatic metastasis after neoadjuvant chemotherapy // Immunobiology. – 2017. – Том 222, вып.1. – 101-109. - DOI: 10.1016/j.imbio.2016.08.001
7. Buldakov, M., Zavyalova, M., Krakhmal, N.,Telegina, N., Vtorushin, S., Mitrofanova, I., Riabov, V., Yin, S., Song, B., Cherdyntseva, N, Kzhyshkowska, J. CD68+, but not stabilin-1+ tumor associated macrophages in gaps of ductal tumor structures negatively correlate with the lymphatic metastasis in human breast cancer (Article) // Immunobiology. – 2017. - Volume 222, Issue 1, 1 January . - Pages 31-38
8. Tashireva LA, Denisov EV, Gerashchenko TS, Pautova DN, Buldakov MA, Zavyalova MV, Kzhyshkowska J, Cherdyntseva NV, Perelmuter VM. Intratumoral heterogeneity of macrophages and fibroblasts in breast cancer is associated with the morphological diversity of tumor cells and contributes to lymph node metastasis // Immunobiology. 2017 Apr;222(4):631-640.- doi: 10.1016/j.imbio.2016.11.012.
9. Savelieva, O.E., Tashireva, L.A., Buldakov, M.A., Zavyalova, M.V., Perelmuter, V.M.CXCR4 expression in different subsets of CTCs and single (detached) breast cancer cells // Siberian Journal of Oncology, 2018, 17(4), с. 75-80
10. Bragina, O., Larkina, M., Stasyuk, E., Deyev, S., Buldakov, M. In vitro evaluation of a specific radiochemical compound based on 99mTc-labeled DARPinG3 for radionuclide imaging of tumors overexpressing Her-2/neu // AIP Conference Proceedings, 2017, 1882, 020007
11. Evtina, A.A., Nekhoroshev, V.O., Buldakov, M.A., Landl, N.V., Korolev, Y.D. Inhibition of tumor cell proliferation in vitro using atmospheric-pressure plasma jet // Journal of Physics: Conference Series, 2020, 1611(1), 012052 doi:10.1088/1742-6596/1611/1/012052
12. Zharkova, L.P., Romanchenko, I.V., Buldakov, M.A., Bolshakov, M.A., Rostov, V.V. Mitochondrial Membrane Permeability after Nanosecond Electromagnetic Pulsed Exposure // Proceedings - 2018 20th International Symposium on High-Current Electronics, ISHCE 2018, 2018, с. 220P, 8521236
13. Buldakov, M.A., Tretyakova, M.S., Ryabov, V.B., Rostov, V.V., Cherdyntseva, N.V. Macrophage and tumor cell responses to repetitive pulsed X-ray radiation // Journal of Physics: Conference Series, 2017, 830(1), 012045
14. Cherdyntseva, N. V.; Mitrofanova, I. V.; Buldakov, M. A. Macrophages and tumor progression: on the way to macrophage-specif therapy // Byulleten Sibirskoy Meditsiny, 2017, 16(4), pp. 61-74