Personalities

Svetlana A. Ivanova

MD, Professor, Deputy Director for Research of Mental Health Research Institute of Tomsk NRMC, Head of the Laboratory of Molecular Genetics and Biochemistry of mental Health Research Institute, Professor of the Department of Psychiatry, Addiction Psychiatry and Psychotherapy of Siberian State Medical University.

Contact information

e-mail: ivanovaniipz@gmail.com
tel.: 8 (3822) 72-31-77; 72-43-79
fax: 8 (3822) 72-44-25

Brief Biography

After graduating from the medical and biological faculty of the Tomsk Medical Institute in 1987, Svetlana Aleksandrovna was sent to work at the Mental Health Research Institute, where she still works. In 1990 she received the academic degree of Candidate of Medical Sciences, and in 2001 she defended her doctoral dissertation. Since 2003 - Head of the Laboratory of Cellular and Molecular Biological Research, which was subsequently renamed the Laboratory of Molecular Genetics and Biochemistry. In 2008, she was awarded the academic title of professor in the specialty of psychiatry. Since 2013, she has been working as Deputy Director for Research at Mental Health Research Institute.

Research Interests

Molecular psychiatry, genetics, pharmacogenetics, biochemistry, biomarkers of mental disorders, translational psychiatry

Achievements, awards, and grants

1. Medal of the Ministry of Science and Higher Education of the Russian Federation “For contribution to the implementation of state policy in the field of scientific and technological development” (2021)

2. Honorary title "Professor of the Year" (2020)

3. Certificate of honor from the Presidium of the Russian Academy of Sciences (2017),

4. Gratitude and Certificate of Honor from the Presidium of the Siberian Branch of the Russian Academy of Medical Sciences (2001),

5. Gratitude from the Russian Academy of Medical Sciences (2004),

6. Certificate of Honor from the Russian Academy of Medical Sciences (2007),

7. Certificate of Honor from the Administration of the Tomsk Region (2009),

8. Certificate of Honor from the Council of Rectors of Universities in Tomsk (2014),

9. Anniversary medal “70 years of the Tomsk region” (2014),

10. Medal "For Achievement" (2016),

11. Prize of the laureate of the competition of the administration of the Tomsk Region in the field of education and science, healthcare and culture (2016).

12. Prize of the laureate of the competition of the administration of the Tomsk Region in the field of education and science, health and culture as the leader of the team of authors (for the study “Mechanisms of apoptosis under conditions of oxidative stress in mental and addictive disorders”) (2009).

13. Prize of the laureate of the competition of the administration of the Tomsk Region in the field of education and science, healthcare and culture as part of the team of authors (2007).

14. Laureate Award of the Regional Public Fund for the Promotion of Domestic Medicine and the Presidium of the Russian Academy of Medical Sciences in the field of medicine in the category “Clinical Medicine” (2001-2002).

15. Prize of the laureate of the competition of the administration of the Tomsk Region among young scientists in the field of science and education (1999).

Memberships

1. Member of the European College of Neuropsychopharmacology (ECNP),

2. International College of Neuropsychopharmacology (CINP),

3. Member of the Board of the Russian Society of Psychiatrists,

4. Chairman of the section “Molecular Psychiatry” of the Russian Society of Psychiatrists,

5. Member of the World Psychiatric Association (WPA) and member of the scientific committee of the International Association of Ethnopsychologists and Ethnopsychotherapists (IAEE),

6. World Society of Biological Psychiatry,

7. World Association of Cultural Psychiatry

8. Member of the educational committee of the International College of Neuropsychopharmacology (2016-2022);

9. Member of the public organization “Tomsk Professorial Assembly”.

Membership in the Councils: Deputy Chairman of the Academic Council of Mental Health Research Institute of Tomsk National Research Medical Center, member of the Academic Council of Tomsk National Research Medical Center, member of the Council for Defense of Doctoral and Candidate Dissertations 24.1.215.05 in specialty 3.1.17 - “Psychiatry and Narcology” (biological sciences, medical sciences) at Mental Health Research Institute, Tomsk National Research Medical Center; member of the Dissertation Council 24.1.215.03 in specialty 1.5.7. Genetics (biological sciences, medical sciences) at Medical Genetics Research Institute of Tomsk National Research Medical Center.

Participation in editorial boards: deputy editor-in-chief of the journal “Siberian Herald of Psychiatry and Addiction Psychiatry” (Tomsk), member of the biological psychiatry committee of the editorial board of the monthly scientific and practical journal “Mental Health” (Moscow)

Participation in expert councils: expert of the Russian Science Foundation (since 2014), expert of the Russian Academy of Sciences (since 2016).

Grants and projects

1. Grant of RSF 22-25-00633 “Growth factors and chemokines in schizophrenia: new approaches to data analysis” 2022-2023 (supervisor);
2. Grant of RSF 22-15-00084 “Unipolar and bipolar depression: transdiagnosticity or specificity of potential clinical, neurophysiological, molecular biological and metabolomic markers?” 2022-2024 (principal investigator);
3. Grant of RSF 19-15-00023 “Clinical features and search for potential biomarkers of comorbidity of alcoholism and affective disorders” 2019-2021 (investigator);
4. Grant of RSF 18-15-00011 “Schizophrenia combined with metabolic syndrome: clinical and constitutional factors and molecular markers” (2018-2020) (supervisor);
5. Grant of RSF 18-15-00082 “Development of the scientific foundations of robotic neuromyorehabilitation” (2018-2020) (principal investigator);
6. Contract 6045 dated June 27, 2019 for the implementation of research work “The role of polymorphic variants of serotonin receptor genes in the development of antipsychotic-induced tardive dyskinesia in schizophrenia”, 2019 (supervisor);
7. Federal Targeted Program Contract 14.601.21.0015 on the topic “Development of a forecast for the implementation of the priority of scientific and technological development, defined by paragraph 20c “Transition to personalized medicine, high-tech healthcare and health-saving technologies, including through the rational use of drugs (primarily antibacterial)” Strategies scientific -technological development of the Russian Federation", 2017 (investigator);
8. Project 30 “Integrated approach to creating a new generation of antipsychotics” of the Basic Scientific Research Program of the SB RAS II.1 “Integration Interdisciplinary Research”, block “Clinical molecular genetic studies of STEP, D2R, GSK-3β and DISC1 in schizophrenia”, 2018-2020 (supervisor of the block);
9. Project “Development of technology for predicting side metabolic effects of antipsychotic therapy in schizophrenia based on studying the role of endothelial nitric oxide synthase” of the program of the Presidium of the Russian Academy of Sciences “Basic research for biomedical technologies”, 2018-2020 (supervisor);
10. Grant of RFBR 17-29-06035 ofi_m “New approaches to the pharmacogenetics of antipsychotic-induced hyperprolactinemia in patients with schizophrenia” 2017-2020 (supervisor);
11. Contract 5007 dated June 22, 2017 for the implementation of research work “The role of neurotransmitter transporter gene polymorphisms in the development of drug-induced movement disorders in schizophrenia and Parkinson’s disease”, 2017, (supervisor);
12. Grant of RSF 14-15-00480 "Search for key biomarkers of the pathogenesis of socially significant endogenous mental disorders", 2014-2016 (supervisor);
13. Grant of RSF 14-35-00023 "Laboratory of pharmacogenetic research of personalized therapy for mental and neurodegenerative disorders", 2014-2016 (principal investiagtor);
14. Grant of RFBR 14-04-01157-a “Search for biomarkers of depressive and affective disorders”, 2014-2016 (supervisor);
15. Grant of RFBR 17-29-02205 ofi_m "Development of a molecular genetic panel of depressive disorders based on polymorphisms of neuronal kinase genes, neurotrophic proteins and serotonergic system genes", 2017-2019 (investigator);
16. Contract 4110 dated August 25, 2016 for the implementation of research work “Studying the association of polymorphism of genes of transporters of neurotransmitter systems in patients with depressive spectrum disorders with response to antidepressant therapy”, 2016 (supervisor)
17. Grant of RHSF 14-04-00531 a “Psychosocial, ethnocultural and genetic determinants of alcohol dependence among representatives of the indigenous population of Siberia”, 2014-2016, (investigator);
18. Contract 3855 dated July 7, 2015 for the implementation of research work “Study of associations of polymorphisms of neurotransmitter systems transporter genes in patients with schizophrenia with side effects of antipsychotic therapy (hyperprolactinemia)”, 2015, (supervisor).
19. Agreement on the topic of research between the Department of Pharmacotherapy and Pharmaceutical Care of the Research Institute of Pharmacy in Groningen (Netherlands) and Mental Health Research Institute of the Siberian Branch of the Russian Academy of Medical Sciences “Development of a test for the determination of clozapine in a dried blood spot”, 2013-2015 (co-supervisor);
20. Grant of RFBR 11-04-01102-a “Study of the association of PIP5K2A kinase gene polymorphism with socially significant mental and behavioral disorders”, 2011-2013 (supervisor);
21. Grant of RHSF 11-36-00213a1 “Serotonin system in the modulation of aggressive and depressive behavior: development of new approaches to the prediction, diagnosis and treatment of mental disorders”, 2011-2013 (supervisor);
22. Joint integration project of the SB RAS and SB RAMS No. 5 “Medical proteomics: search for markers of mental disorders” (2012-2014) (co-supervisor);
23. Contract dated 05/31/2011 between Brainlabs BV (Holland), the Department of Nuclear Medicine of the Medical Center of the University of Groningen and the Mental Health Research Institute of the Siberian Branch of the Russian Academy of Medical Sciences on the topic “Validation of biomarkers of depression”, 2011-2013 (co-supervisor);
24. Grant of RHSF 11-06-00550a “The role of psychological and neuroendocrine factors in the formation of an aggressive pattern of behavior in the penitentiary system”, 2012-2013; (responsible investigator);
25. Federal Targeted Program “Development of a set of markers of major socially significant mental disorders based on the study of molecular genetic mechanisms of dysregulation of neuronal protein kinase signaling pathways”, State Contract 8140 (2012-2013) (responsible investigator);
26. Federal Target Program “Prevention and Combating Socially Significant Diseases”, K -32-NIR/118-6 (2011) “Development of models for diagnosis, prognosis and evaluation of the effectiveness of therapy for affective and addictive disorders based on immunophysiological, molecular biological and molecular genetic approaches” (responsible investigator);
27. Federal Targeted Program, state contract K-16-NIR/46-8 (2010) “Development of methods for assessing the quality of specialized medical care for patients with mental disorders based on the use of clinical, immunophysiological and biochemical criteria” (responsible investigator);
28. Federal Targeted Program, state contract 06/957 (2007) “Clinical-immunological, immuno-physiological and molecular-biological mechanisms of pathogenetic therapy of mental disorders” within the framework of the subprogram “Mental disorders” of the Federal Targeted Program “Prevention and control of socially significant diseases (2007–2011)" (responsible investigator).

Monographs and chapters

1.    Simutkin GG, Bokhan NA, Ivanova SA. (2023). [Probabilistic diagnosis of bipolar affective disorder: modern approaches, possibilities and limitations]. Tomsk: Integral Casework. 162 p. https://elibrary.ru/item.asp?id=54904236 (in Russian).

2.    Ivanova SA, Kornetova EG, Boyko AS, Mednova IA, Khamina VV, Semke AV, Bokhan NA. (2021). [Metabolic syndrome in patients with schizophrenia: clinical and constitutional features and molecular markers]. Tomsk: Integral Casework. 158 p. https://elibrary.ru/item.asp?id=45667556 (in Russian).

3.    Bokhan NA, Roshchina OV, Schastnyy ED, Simutkin GG, Ivanova SA. (2021). Comorbidity of affective disorders and alcohol dependence. Tomsk: Integral Casework. 143 p. https://elibrary.ru/item.asp?id=49203268 (in Russian).

4.    Kornetova EG, Ivanova SA, Tiguntsev VV, Boyko AS, Lobacheva OA, Kornetov AN, Semke AV. (2019). [Antipsychotic-induced hyperprolactinemia in patients with schizophrenia: social, clinical, immunological and therapeutic features]. Tomsk: Integral Casework. 108 p. https://elibrary.ru/item.asp?id=40512682 (in Russian).

5.    Kornetova EG, Semke AV, Kornetov AN, Ivanova SA, Lobacheva OA, Semenyuk KA, Boiko AS, Bokhan NA. (2018). [Schizophrenia: biopsychosocial model and constitutional-biological approach]. Tomsk: Integral Casework. 174 p. https://elibrary.ru/item.asp?id=35051499 (in Russian).

6.    Ivanova SA, Losenkov IS, Levchuk LA, Boiko AS, Vyalova NM, Simutkin GG, Bokhan NA. (2018). [Depressive disorders: hypotheses of pathogenesis and potential biological markers]. Mental Health Research Institute, Tomsk National Research Medical Center RAS. Novosibirsk: Publishing House SB RAS. 199 p. https://elibrary.ru/item.asp?id=41559841 (in Russian).

7.    Avtenyuk AS, Aksenova IO, ,…., Ivanova S.,…. Chomsky AN. (2018). [Diagnosis and treatment of mental and narcological disorders: modern approaches]. St. Petersburg: Publishing and Printing Company Costa. 448 p. https://elibrary.ru/item.asp?id=36791457 (in Russian).

8.    Boiko AS, Bokhan NA, Buneva VN, Vetlugina TP, Zozulya SA, Ivanova SA, Klyushnik TP, Kornetova EG, Losenkov IS, Oleinik IV, Semke AV, Smirnova LP, Uzbekov MG, Fedorenko OYu. (2017). [Biological markers of schizophrenia: search and clinical application]. NA Bokhan, SA Ivanova, eds. Novosibirsk: Publishing House SB RAS. 148 p. https://elibrary.ru/item.asp?id=28393577 (in Russian).

9.    Ivanova SA, Fedorenko OYu, Bokhan NA, Loonen A. (2015). [Pharmacogenetics of tardive dyskinesia]. Tomsk: Publishing house New Printing Technologies. 120 p. https://elibrary.ru/item.asp?id=23773926 (in Russian).

10. Fedorenko OYu, Ivanova SA, Bokhan NA. (2013). [Genetic disorders of protein kinases in mental disorders using the PIP5K2A, SGK1 and GSK3 model]. Saarbrücken: Palmarium Academic Publishing. 93 p. https://elibrary.ru/item.asp?id=21334688 (in Russian).

11. Bokhan NA, Ivanova SA, Levchuk LA. (2013). [Serotonin system in the modulation of depressive and aggressive behavior]. Tomsk: Ivan Fedorov. 104 p. https://elibrary.ru/item.asp?id=20899270 (in Russian).

12. Ivanova SA, Toshchakova VA, Bokhan NA. (2014). [Hormonal factors in the regulation of aggression]. Tomsk: Publishing House Ivan Fedorov. 108 p. https://elibrary.ru/item.asp?id=21242643 (in Russian).

13. Loonen Anton JM, Schellekens Arnt FA and Ivanova Svetlana A (2016). Circuits regulating pleasure and happiness: a focus on addiction, beyond the ventral striatum. Chapter in the book “Recent Advances in Drug Addiction Research and Clinical Applications” (edited by William M. Meil and Christina L. Ruby), InTech. P. 1-20. DOI: 10.5772/62707 (http://www.intechopen.com/books/recent-advances-in-drug-addiction-research-and-clinical-applications... -addiction-beyond-the-ventral-striatum)

14. Loonen Anton JM and Ivanova Svetlana A. (2016). Circuits regulating pleasure and happiness in schizophrenia: The neurobiological mechanism of delusions. Chapter 6 in book Schizophrenia Treatment - The New Facets Edited by Yu-Chih Shen 178 pages, Publisher: InTech. DOI: 10.5772/62958. P.109-134 https://www.intechopen.com/books/schizophrenia-treatment-the-new-facets/circuits-regulating-pleasure... delusio

15. Semke VYa, Gutkevich EV, Ivanova SA. (2008). [Psychosocial and biological factors of mental disadaptation in the model of neurotic disorders]. Tomsk. 204 p. https://elibrary.ru/item.asp?id=19037928 (in Russian).

16. Vetlugina TP, Ivanova SA, Nevidimova TI. (2001). [Clinical immunology in psychiatry and narcology]. Short course of lectures for students of the Faculty of Education and Science in the specialty “Psychiatry”. Tomsk. 92 p. https://elibrary.ru/item.asp?id=21334715 (in Russian).

17. Abolonin AF, Aksenov MM, Bokhan NA, Gusev SI, Gutkevich EV, Didenko AV, Dmitrieva TB, Epachintseva EM Zhiginas N.., Ivanova SA, Kononets A., Krivtsov A., Makushkin EV, Malkin DA, Mandel A. Nasrullaev FS, Odarchenko SS, Oshevsky DS, Semke AV, Semke VYa et al. (2007). [Penitentiary psychology and psychopathology]. Handbook in two volumes. Moscow, Tomsk, Kemerovo. Volume 1. 576 p. https://elibrary.ru/item.asp?id=24181344 (in Russian).

18. Semke VYa, Vetlugina TP, Nevidimova TI, Ivanova SA, Bokhan NA. (2003). [Clinical psychoneuroimmunology]. Tomsk. 300 p. https://elibrary.ru/item.asp?id=19178602 (in Russian).

19. Volodin NN, Degtyareva MV, Dimitryuk SV, Ivanova SA, Kalinina NM, Katinas EB, Ketlinsky SA, Kozhokar Yu., Kozlov VK., Komarets SA, Lavrenova GV, Lobzin YuV, Nevidimova TI, Nesterova IV, Pluzhnikov MS, Poznyak AL, Polevshchikov AV, Popovich A., Serebryanaya NB, Ses TP et al. (2002). [Guide to immunotherapy for practitioners]. St. Petersburg, Dialog Publishing House. 480 p. https://elibrary.ru/item.asp?id=38538072 (in Russian). 

Main Publications

1.    Chernonosov AA, Mednova IA, Levchuk LA, Mazurenko EO, Roschina OV, Simutkin GG, Bokhan NA, Koval VV, Ivanova SA. Untargeted Plasma Metabolomic Profiling in Patients with Depressive Disorders: A Preliminary Study. Metabolites. 2024 Feb 6;14(2):110. doi: 10.3390/metabo14020110. PMID: 38393002; https://pubmed.ncbi.nlm.nih.gov/38393002/

2.    Mednova, I.A.; Pozhidaev, I.V.; Tiguntsev, V.V.; Bocharova, A.V.; Paderina, D.Z.; Boiko, A.S.; Fedorenko, O.Y.; Kornetova, E.G.; Bokhan, N.A.; Stepanov, V.A.; Svetlana A. Ivanova  NOS1AP Gene Variants and Their Role in Metabolic Syndrome: A Study of Patients with Schizophrenia. Biomedicines 2024, 12, 627. https://doi.org/10.3390/biomedicines12030627

3.    Seregin AA, Smirnova LP, Dmitrieva EM, Zavialova MG, Simutkin GG, Ivanova SA. Differential Expression of Proteins Associated with Bipolar Disorder as Identified Using the PeptideShaker Software. Int J Mol Sci. 2023 Oct 17;24(20):15250. doi: 10.3390/ijms242015250 https://pubmed.ncbi.nlm.nih.gov/37894929/

4.    Levchuk LA, Roschina OV, Mikhalitskaya EV, Epimakhova EV, Simutkin GG, Bokhan NA, Ivanova SA. Serum Levels of S100B Protein and Myelin Basic Protein as a Potential Biomarkers of Recurrent Depressive Disorders. J Pers Med. 2023 Sep 21;13(9):1423. doi: 10.3390/jpm13091423. https://pubmed.ncbi.nlm.nih.gov/37763190/

5.    Mikhalitskaya EV, Vyalova NM, Ermakov EA, Levchuk LA, Simutkin GG, Bokhan NA, Ivanova SA. Association of Single Nucleotide Polymorphisms of Cytokine Genes with Depression, Schizophrenia and Bipolar Disorder. Genes (Basel). 2023 Jul 17;14(7):1460. doi: 10.3390/genes14071460. https://pubmed.ncbi.nlm.nih.gov/37510364/

6.    Kozyrev EA, Ermakov EA, Boiko AS, Mednova IA, Kornetova EG, Bokhan NA, Ivanova SA. Building Predictive Models for Schizophrenia Diagnosis with Peripheral Inflammatory Biomarkers. Biomedicines. 2023 Jul 14;11(7):1990. doi: 10.3390/biomedicines11071990. https://pubmed.ncbi.nlm.nih.gov/37509629/

7.    Ermakov EA, Melamud MM, Boiko AS, Kamaeva DA, Ivanova SA, Nevinsky GA, Buneva VN. Association of Peripheral Inflammatory Biomarkers and Growth Factors Levels with Sex, Therapy and Other Clinical Factors in Schizophrenia and Patient Stratification Based on These Data. Brain Sci. 2023 May 22;13(5):836. doi: 10.3390/brainsci13050836 https://pubmed.ncbi.nlm.nih.gov/37239308/

8.    Kamaeva DA, Kazantseva DV, Boiko AS, Mednova IA, Smirnova LP, Kornetova EG, Ivanova SA. The Influence of Antipsychotic Treatment on the Activity of Abzymes Targeting Myelin and Levels of Inflammation Markers in Patients with Schizophrenia. Biomedicines. 2023 Apr 14;11(4):1179. doi: 10.3390/biomedicines11041179. https://pubmed.ncbi.nlm.nih.gov/37189796/

9.    Boiko AS, Mednova IA, Kornetova EG, Bokhan NA, Ivanova SA. Serum Growth Factors in Schizophrenia Patients. Curr Issues Mol Biol. 2023 Apr 7;45(4):3291-3301. doi: 10.3390/cimb45040215. https://pubmed.ncbi.nlm.nih.gov/37185739/

10. Epimakhova EV, Smirnova LP, Kazantseva DV, Kamaeva DA, Ivanova SA. Different Directions of Effects of Polyclonal IgG Antibodies from Patients with Schizophrenia and Healthy Individuals on Cell Death In Vitro: A Pilot Study. Curr Issues Mol Biol. 2023 Apr 6;45(4):3168-3179. doi: 10.3390/cimb45040206 https://pubmed.ncbi.nlm.nih.gov/37185730/

11. Boiko AS, Mednova IA, Kornetova EG, Semke AV, Bokhan NA, Ivanova SA. Cell Adhesion Molecules in Schizophrenia Patients with Metabolic Syndrome. Metabolites. 2023 Mar 2;13(3):376. doi: 10.3390/metabo13030376. https://pubmed.ncbi.nlm.nih.gov/36984816/

12. Poltavskaya EG, Kornetova EG, Freidin MB, Pozhidaev IV, Paderina DZ, Bocharova AV, Semke AV, Bokhan NA, Ivanova SA, Fedorenko OY. The Role of Glutamatergic Gene Polymorphisms in the Clinical Phenotypes of Schizophrenia. Genes (Basel). 2023 Feb 24;14(3):575. doi: 10.3390/genes14030575. https://pubmed.ncbi.nlm.nih.gov/36980845/

13. Ermakov EA, Mednova IA, Boiko AS, Buneva VN, Ivanova SA. Chemokine Dysregulation and Neuroinflammation in Schizophrenia: A Systematic Review. Int J Mol Sci. 2023 Jan 22;24(3):2215. doi: 10.3390/ijms24032215 https://pubmed.ncbi.nlm.nih.gov/36768537/

14. Mednova IA, Levchuk LA, Boiko AS, Roschina OV, Simutkin GG, Bokhan NA, Loonen AJM, Ivanova SA. Cytokine level in patients with mood disorder, alcohol use disorder and their comorbidity. World J Biol Psychiatry. 2023 Mar;24(3):243-253. doi: 10.1080/15622975.2022.2095439. https://pubmed.ncbi.nlm.nih.gov/35818961/

15. Aftanas LI, Filimonova EA, Anisimenko MS, Berdyugina DA, Rezakova MV, Simutkin GG, Bokhan NA, Ivanova SA, Danilenko KV, Lipina TV. The habenular volume and PDE7A allelic polymorphism in major depressive disorder: preliminary findings. World J Biol Psychiatry. 2023 Mar;24(3):223-232. doi: 10.1080/15622975.2022.2086297. https://pubmed.ncbi.nlm.nih.gov/35673941/

16. Mednova IA, Boiko AS, Kornetova EG, Semke AV, Bokhan NA, Ivanova SA. Cytokines as Potential Biomarkers of Clinical Characteristics of Schizophrenia. Life (Basel). 2022 Nov 25;12(12):1972. doi: 10.3390/life12121972. https://pubmed.ncbi.nlm.nih.gov/36556337/

17. Melamud MM, Ermakov EA, Boiko AS, Kamaeva DA, Sizikov AE, Ivanova SA, Baulina NM, Favorova OO, Nevinsky GA, Buneva VN. Multiplex Analysis of Serum Cytokine Profiles in Systemic Lupus Erythematosus and Multiple Sclerosis. Int J Mol Sci. 2022 Nov 10;23(22):13829. doi: 10.3390/ijms232213829. https://pubmed.ncbi.nlm.nih.gov/36430309/

18. Boiko AS, Mednova IA, Kornetova EG, Goncharova AA, Semke AV, Bokhan NA, Ivanova SA. Metabolic Hormones in Schizophrenia Patients with Antipsychotic-Induced Metabolic Syndrome. J Pers Med. 2022 Oct 5;12(10):1655. doi: 10.3390/jpm12101655. https://pubmed.ncbi.nlm.nih.gov/36294794/

19. Mednova IA, Chernonosov AA, Kornetova EG, Semke AV, Bokhan NA, Koval VV, Ivanova SA. Levels of Acylcarnitines and Branched-Chain Amino Acids in Antipsychotic-Treated Patients with Paranoid Schizophrenia with Metabolic Syndrome. Metabolites. 2022 Sep 9;12(9):850. doi: 10.3390/metabo12090850. https://pubmed.ncbi.nlm.nih.gov/36144254/

20. Mednova IA, Smirnova LP, Vasilieva AR, Kazantseva DV, Epimakhova EV, Krotenko NM, Semke AV, Ivanova SA. Immunoglobulins G of Patients with Schizophrenia Protects from Superoxide: Pilot Results. J Pers Med. 2022 Sep 1;12(9):1449. doi: 10.3390/jpm12091449. https://pubmed.ncbi.nlm.nih.gov/36143234/

21. Loonen AJM, Ivanova SA.  Circuits regulating pleasure and happiness - focus on potential biomarkers for circuitry including the habenuloid complex. Acta Neuropsychiatr. 2022 May 19:1-11. doi: 10.1017/neu.2022.15 https://pubmed.ncbi.nlm.nih.gov/35587050/

22. Boiko AS, Pozhidaev IV, Paderina DZ, Mednova IA, Goncharova AA, Fedorenko OY, Kornetova EG, Semke AV, Bokhan NA, Loonen AJM, Ivanova SA. Gene Polymorphisms of Hormonal Regulators of Metabolism in Patients with Schizophrenia with Metabolic Syndrome. Genes. 2022; 13(5):844. https://doi.org/10.3390/genes13050844 https://pubmed.ncbi.nlm.nih.gov/35627229/

23. Geers LM, Ochi T, Vyalova NM, Losenkov IS, Paderina DZ, Pozhidaev IV, Simutkin GG, Bokhan NA, Wilffert B, Touw DJ, Loonen AJM, Ivanova SA.          Influence of eight ABCB1 polymorphisms on antidepressant response in a prospective cohort of treatment-free Russian patients with moderate or severe depression: An explorative psychopharmacological study with naturalistic design Hum Psychopharmacol 2022 May;37(3):e2826. doi: 10.1002/hup.2826. https://pubmed.ncbi.nlm.nih.gov/34788473/

24. Ermakov EA, Melamud MM, Buneva VN, Ivanova SA. Immune System Abnormalities in Schizophrenia: An Integrative View and Translational Perspectives. Front Psychiatry. 2022 Apr 25;13:880568. doi: 10.3389/fpsyt.2022.880568. https://pubmed.ncbi.nlm.nih.gov/35546942/

25. Melamud Mark M., Ermakov Evgeny A., Boiko Anastasiia S., Parshukova Daria A., Sizikov Alexey E., Ivanova Svetlana A., Nevinsky Georgy A., Buneva Valentina N. Serum cytokine levels of systemic lupus erythematosus patients in the presence of concomitant cardiovascular diseases // Endocrine, Metabolic & Immune Disorders - Drug Targets 2022; 22 . https://dx.doi.org/10.2174/1871530322666220304214512

26. Paderina DZ, Boiko AS, Pozhidaev IV, Mednova IA, Goncharova AA, Bocharova AV, Fedorenko OY, Kornetova EG, Semke AV, Bokhan NA, Loonen AJM, Ivanova SA. The Gender-Specific Association of DRD2 Polymorphism with Metabolic Syndrome in Patients with Schizophrenia. Genes (Basel). 2022 Jul 23;13(8):1312. doi: 10.3390/genes13081312  https://pubmed.ncbi.nlm.nih.gov/35893053/

27. Fedorenko OY, Paderina DZ, Kornetova EG, Poltavskaya EG, Pozhidaev IV, Goncharova AA, Freidin MB, Bocharova AV, Bokhan NA, Loonen AJM, Ivanova SA. Genes of the Glutamatergic System and Tardive Dyskinesia in Patients with Schizophrenia. Diagnostics (Basel). 2022 Jun 22;12(7):1521. doi: 10.3390/diagnostics12071521. https://pubmed.ncbi.nlm.nih.gov/35885427/

28. Kamaeva DA, Smirnova LP, Vasilieva SN, Kazantseva DV, Vasilieva AR, Ivanova SA. Catalytic Antibodies in Bipolar Disorder: Serum IgGs Hydrolyze Myelin Basic Protein. Int J Mol Sci. 2022 Jul 2;23(13):7397. doi: 10.3390/ijms23137397 https://pubmed.ncbi.nlm.nih.gov/35806400/

29. Mednova IA, Chernonosov AA, Kasakin MF, Kornetova EG, Semke AV, Bokhan NA, Koval VV, Ivanova SA. Amino Acid and Acylcarnitine Levels in Chronic Patients with Schizophrenia: A Preliminary Study. Metabolites. 2021; 11(1):34. https://doi.org/10.3390/metabo11010034

30.  A. Levchenko,  A. Kanapin,  A.Samsonova,  O.Yu. Fedorenko,  E.G.Kornetova, T.Nurgaliev, G.E.Mazo,  A. V.Semke , A.O.Kibitov, N. A.Bokhan, R.R.Gainetdinov, S. A.Ivanova A genome-wide association study identifies a gene network associated with paranoid schizophrenia and antipsychotics-induced tardive dyskinesia / Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2021 Mar 8;105:110134. doi: 10.1016/j.pnpbp.2020.110134.  https://pubmed.ncbi.nlm.nih.gov/33065217/

31.  Loonen AJ, Ivanova SA. Neurobiological mechanisms associated with antipsychotic drug-induced dystonia. J Psychopharmacol. 2021 Jan;35(1):3-14. doi: 10.1177/0269881120944156. https://pubmed.ncbi.nlm.nih.gov/32900259/

32. Paderina DZ, Boiko AS, Pozhidaev IV, Bocharova AV, Mednova IA, Fedorenko OY, Kornetova EG, Loonen AJM, Semke AV, Bokhan NA, Ivanova SA. Genetic Polymorphisms of 5-HT Receptors and Antipsychotic-Induced Metabolic Dysfunction in Patients with Schizophrenia. Journal of Personalized Medicine. 2021; 11(3):181. https://doi.org/10.3390/jpm11030181

33. Boiko, A.S.; Mednova, I.A.; Kornetova, E.G.; Gerasimova, V.I.; Kornetov, A.N.; Loonen, A.J.M.; Bokhan, N.A.; Ivanova, S.A. Cytokine Level Changes in Schizophrenia Patients with and without Metabolic Syndrome Treated with Atypical Antipsychotics. Pharmaceuticals 2021, 14, 446. https://doi.org/10.3390/ph14050446 

34. Elena G. Kornetova, Alexander N. Kornetov, Irina A. Mednova, Anastasia A. Goncharova, Valeria I. Gerasimova, Ivan V. Pozhidaev, Anastasia S. Boiko, Arkadiy V. Semke, Anton J.M. Loonen, Nikolay A. Bokhan, Svetlana A. Ivanova (2021). Comparative characteristics of the metabolic syndrome prevalence in patients with schizophrenia in three Western Siberia psychiatric hospitals. Front. Psychiatry. 12:661174021. doi: 10.3389/fpsyt.2021.661174 https://pubmed.ncbi.nlm.nih.gov/34276438/

35. Smirnova LP, Yarnykh VL, Parshukova DA, Kornetova EG, Semke AV, Usova AV, Pishchelko AO, Khodanovich MY, Ivanova SA.  Global hypomyelination of the brain white and gray matter in schizophrenia: quantitative imaging using macromolecular proton fraction. Transl Psychiatry 11, 365 (2021). https://doi.org/10.1038/s41398-021-01475-8

36. Ochi, T.; Vyalova, N.M.; Losenkov, I.S.; Paderina, D.Z.; Pozhidaev, I.V.; Loonen, A.J.M.; Simutkin, G.G.; Bokhan, N.A.; Wilffert, B.; Ivanova, S.A. Preliminary Pharmacogenetic Study to Explore Putative Dopaminergic Mechanisms of Antidepressant Action. J. Pers. Med. 2021, 11, 731. https://doi.org/10.3390/jpm11080731

37. Boiko AS, Pozhidaev IV, Paderina DZ, Bocharova AV, Mednova IA, Fedorenko OY, Kornetova EG, Loonen AJM, Semke AV, Bokhan NA, Ivanova SA. Search for Possible Associations of FTO Gene Polymorphic Variants with Metabolic Syndrome, Obesity and Body Mass Index in Schizophrenia Patients. Pharmgenomics Pers Med. 2021;14:1123-1131 https://doi.org/10.2147/PGPM.S327353 

38. Galkin S.A., Roshchina O.V., Kisel N.I., Ivanova S.A., Bokhan N.A. Clinical and Neurophysiological Characteristics of Alcohol Dependence and Its Comorbidity with Affective Disorders. Neurosci Behav Physi. 2021. Т. 51. № 6. С. 720-723 https://link.springer.com/article/10.1007/s11055-021-01127-w

39. Fedorenko O.Yu., Mikhalitskaya E.V., Toshchakova V.A., Loonen A.J.M., Bokhan N.A., Ivanova S.A. Association of PIP4K2A Polymorphisms with Alcohol Use Disorder. Genes 2021, 12(10), 1642; https://doi.org/10.3390/genes12101642

40. Roschina, O.V.; Levchuk, L.A.; Boiko, A.S.; Michalitskaya, E.V.; Epimakhova, E.V.; Losenkov, I.S.; Simutkin, G.G.; Loonen, A.J.M.; Bokhan, N.A.; Ivanova, S.A. Beta-Endorphin and Oxytocin in Patients with Alcohol Use Disorder and Comorbid Depression. J. Clin. Med. 2021, 10, 5696. https://doi.org/10.3390/jcm10235696

41. Loonen AJM, Ochi T, Geers LM, Simutkin GG, Bokhan NA, Touw DJ, Wilffert B, Kornetov AN, Ivanova SA. A New Paradigm to Indicate Antidepressant Treatments. Pharmaceuticals. 2021; 14(12):1288. https://doi.org/10.3390/ph14121288

42. Koroleva ES, Kazakov SD, Tolmachev IV, Loonen AJM, Ivanova SA, Alifirova VM.  Clinical Evaluation of Different Treatment Strategies for Motor Recovery in Poststroke Rehabilitation during the First 90 Days. J Clin Med. 2021 Aug 21;10(16):3718. doi: 10.3390/jcm10163718. https://pubmed.ncbi.nlm.nih.gov/34442014/

43. Poltavskaya EG, Fedorenko OY, Kornetova EG, Loonen AJM, Kornetov AN, Bokhan NA, Ivanova SA. Study of Early Onset Schizophrenia: Associations of GRIN2A and GRIN2BPolymorphisms. Life (Basel). 2021 Sep 22;11(10):997. doi: 10.3390/life11100997. https://pubmed.ncbi.nlm.nih.gov/34685369/

44. Losenkov, I.S., Mulder, N.J.V., Levchuk, L.A., Vyalova, N.M., Loonen, A.J.M., Bosker, F.J., Simutkin, G.G., Boiko, A.S., Bokhan, N.A., Wilffert, B., Hak, E., Schmidt, A.F., Ivanova, S.A. (2020). Association between BDNF gene variant Rs6265 and the severity of depression in antidepressant treatment-free depressed patients. Frontiers in Psychiatry, 11, 38. doi: 10.3389/fpsyt.2020. https://www.frontiersin.org/articles/10.3389/fpsyt.2020.00038/full

45. Geers, L.M., Pozhidaev, I.V., Ivanova, S.A., Freidin, M.B., Schmidt, A.F., Cohen, D., Boiko, A.S., Paderina, D.Z., Fedorenko, O.Y., Semke, A.V., Bokhan, N.A., Wilffert, B., Kosterink, J.G.W., Touw, D.J., Loonen, A.J.M. (2020). Association between eight P-glycoprotein (MDR1/ABCB1) gene polymorphisms and antipsychotic drug-induced hyperprolactinemia. British Journal of Clinical Pharmacology, 86, 1827-1835. doi: 10.1111/bcp.14288  https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bcp.14288

46. Levchuk, L.A., Meeder, E.M.G., Roshchina, O.V., Loonen, A.J.M., Boiko, A.S., Michalitskaya, E.V., Epimakhova, E.V., Losenkov, I.S., Simutkin, G.G., Bokhan, N.A., Schellekens, A.F.A., Ivanova, S.A. (2020). Exploring brain derived neurotrophic factor and cell adhesion molecules as biomarkers for the transdiagnostic symptom anhedonia in alcohol use disorder and comorbid depression. Frontiers in Psychiatry, 11, 296. doi: 10.3389/fpsyt.2020.00296  https://www.frontiersin.org/articles/10.3389/fpsyt.2020.00296/full

47. Levchenko, A., Vyalova, N.M., Nurgaliev, T., Pozhidaev, I.V., Simutkin, G.G., Bokhan, N.A., Ivanova, S.A. (2020). NRG1, PIP4K2A, and HTR2C contain possible genetic biomarkers of several clinical subphenotypes of depression and bipolar disorder. Frontiers in Genetics, 11, 936. doi: 10.3389/fgene.2020.00936 https://www.frontiersin.org/articles/10.3389/fgene.2020.00936/full

48. Smirnova, L.P., Mednova, I.A., Krotenko, N.M., Alifirova, V.M., Ivanova, S.A. (2020). IgG-dependent dismutation of superoxide in patients with different types of multiple sclerosis and healthy subjects. Oxidative Medicine and Cellular Longevity, 2020, 8171020. https://doi.org/10.1155/2020/8171020. https://www.hindawi.com/journals/omcl/2020/8171020/

49. Pozhidaev, I.V., Paderina, D.Z., Fedorenko, O.Y., Kornetova, E.G., Semke, A.V., Loonen, A.J.M., Bokhan, N.A., Wilffert, B., Ivanova, S.A. (2020). 5-hydroxytryptamine receptors and tardive dyskinesia in schizophrenia. Frontiers in Molecular Neuroscience, 13, 63. doi: 10.3389/fnmol.2020.00063 https://www.frontiersin.org/articles/10.3389/fnmol.2020.00063/full

50. Loonen, A.J., Ivanova, S.A. (2020). Neurobiological mechanisms associated with antipsychotic drug-induced dystonia. Journal of Psychopharmacology. 9, 269881120944156. doi: 10.1177/0269881120944156  https://journals.sagepub.com/doi/full/10.1177/0269881120944156

51. Kornetova, E.G., Kornetov, A.N., Mednova, I.A., Lobacheva, O.A., Gerasimova, V.I., Dubrovskaya, V.V., Tolmachev, I.V., Semke, A.V., Loonen, A.J.M., Bokhan, N.A., Ivanova, S.A. (2020). Body fat parameters, glucose and lipid profiles, and thyroid hormone levels in schizophrenia patients with or without metabolic syndrome. Diagnostics, 10, 683. https://doi.org/10.3390/diagnostics10090683 https://www.mdpi.com/2075-4418/10/9/683

52. Boiko, A.S., Ivanova, S.A., Pozhidaev, I.V., Freidin, M.B., Osmanova, D.Z., Fedorenko, O.Y., Semke, A.V., Bokhan, N.A., Wilffert, B., Loonen, A.J.M. (2020). Pharmacogenetics of tardive dyskinesia in schizophrenia: The role of CHRM1 and CHRM2 muscarinic receptors. World Journal of Biological Psychiatry, 21(1), 72-77. doi: 10.1080/15622975.2018.1548780. https://www.tandfonline.com/doi/full/10.1080/15622975.2018.1548780

53. Parshukova, D.A., Smirnova, L.P., Kornetova, E.G., Semke, A.V., Buneva, V.N., Ivanova S.A. (2020). IgG-dependent hydrolysis of myelin basic protein of patients with different courses of schizophrenia. Journal of Immunology Research, 2020, 8986521. https://doi.org/10.1155/2020/8986521.  https://www.hindawi.com/journals/jir/2020/8986521/

54. Pozhidaev, I.V., Boiko, A.S., Loonen, A.J.M., Paderina, D.Z., Fedorenko, O.Yu., Tenin, G., Kornetova, E.G., Semke, A.V., Bokhan, N.A., Wilffert, B., Ivanova, S.A. (2020). Association of cholinergic muscarinic M4 receptor gene polymorphism with schizophrenia. The Application of Clinical Genetics, 13, 97-105. https://doi.org/10.2147/TACG.S247174.  https://pubmed.ncbi.nlm.nih.gov/32368127/

55. Fedorenko, O.Y., Paderina, D.Z., Loonen, A.J.M., Pozhidaev, I.V., Boiko, A.S., Kornetova, E.G., Bokhan, N.A., Wilffert, B., Ivanova, S.A. (2020). Association of ANKK1 polymorphism with antipsychotic-induced hyperprolactinemia. Human Psychopharmacology, 8, e2737. doi: 10.1002/hup.2737.  https://onlinelibrary.wiley.com/doi/full/10.1002/hup.2737

56. Kornetova, E.G.; Kornetov, A.N.; Mednova, I.A.; Lobacheva, O.A.; Gerasimova, V.I.; Dubrovskaya, V.V.; Tolmachev, I.V.; Semke, A.V.; Loonen, A.J.M.; Bokhan, N.A.; Ivanova, S.A. Body Fat Parameters, Glucose and Lipid Profiles, and Thyroid Hormone Levels in Schizophrenia Patients with or without Metabolic Syndrome. Diagnostics 2020, 10 (9), 683. https://doi.org/10.3390/diagnostics10090683

57. Kornetova, E.G., Kornetov, A.N., Mednova, I.A., Dubrovskaya, V.V., Boiko, A.S., Bokhan, N.A., Loonen, A.J.M., Ivanova, S.A. (2019). Changes in body fat and related biochemical parameters associated with atypical antipsychotic drug treatment in schizophrenia patients with or without metabolic syndrome. Frontiers in Psychiatry. 10, 803. https://doi.org/10.3389/fpsyt.2019.00803 https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00803/full

58. Loonen, A.J.M., Ivanova, S.A. (2019). Consider role of glutamatergic habenula-projecting globus pallidus in OCD. Pharmacopsychiatry, 52(4), 203-204. doi: 10.1055/a-0835-6447. https://pubmed.ncbi.nlm.nih.gov/30716772/

59. Loonen, A.J.M., Ivanova, S.A. (2019). Evolution of circuits regulating pleasure and happiness with the habenula in control. CNS Spectrums, 24(2), 233-238. doi: 10.1017/S1092852917000748 https://www.cambridge.org/core/journals/cns-spectrums/article/evolution-of-circuits-regulating-pleasure-and-happiness-with-the-habenula-in-control/F05BF7750A518C6FF61EF15EEDA5035A

60. Fedorenko, O.Y., Golimbet, V.E., Ivanova, S.А., Levchenko, А., Gainetdinov, R.R., ... Lebedev, I.N., … Stepanov, V.A. ...   Kibitov, А.О. (2019). Opening up new horizons for psychiatric genetics in the Russian Federation: moving toward a national consortium. Molecular Psychiatry, 24, 1099-1111. doi: 10.1038/s41380-019-0354-z https://www.nature.com/articles/s41380-019-0354-z

61. Ochi, T., Vyalova, N.M., Losenkov, I.S., Levchuk, L.A., Osmanova, D.Z., Mikhalitskaya, E.V., Loonen, A.J.M., Bosker, F.J., Simutkin, G.G., Bokhan, N.A., Wilffert, B., Ivanova, S.A. (2019). Investigating the potential role of BDNF and PRL genotypes on antidepressant response in depression patients: a prospective inception cohort study in treatment-free patients. Journal of Affective Disorders, 259, 1 December 2019, 432-439. https://doi.org/10.1016/j.jad.2019.08.058 https://www.sciencedirect.com/science/article/pii/S0165032719307402?via%3Dihub

62. Ochi, T., Vyalova, N.M., Losenkov, I.S., Paderina, D.Z., Pozhidaev, I.V., Loonen, A.J., Simutkin, G.G., Bokhan, N.A., Ivanova, S.A., Wilffert, B. (2019). Limited associations between 5-HT receptor gene polymorphisms and treatment response in antidepressant treatment-free patients with depression. Front. Pharmacol., 10, 1462. doi: 10.3389/fphar.2019.01462. https://www.frontiersin.org/articles/10.3389/fphar.2019.01462/full

63. Levchenko, A., Vyalova, N., Pozhidaev, I.V., Boiko, A.S., Osmanova, D.Z., Fedorenko, O.Y., Semke, A.V., Bokhan, N.A., Wilffert, B., Loonen, A.J.M., Ivanova, S.A. (2019). No evidence so far of a major role of AKT1 and GSK3B in the pathogenesis of antipsychotic-induced tardive dyskinesia. Hum Psychopharmacol, Jan 8, e2685. doi: 10.1002/hup.2685. https://onlinelibrary.wiley.com/doi/full/10.1002/hup.2685

64.   Smirnova, L., Seregin, A., Boksha, I., Dmitrieva, E., Simutkin, G., Kornetova, E., Savushkina, O., Letova, A., Bokhan, N., Ivanova, S., Zgoda, V. (2019). The difference in serum proteomes in schizophrenia and bipolar disorder. BMC Genomics, 20, Suppl 3. https://doi.org/10.1186/s12864-019-5848-1 https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5848-1

65. Boiko, A.S., Mednova, I.A., Kornetova, E.G., Semke, A.V., Bokhan, N.A., Loonen, A.J.M., Ivanova, S.A. (2019). Apolipoprotein serum levels related to metabolic syndrome in patients with schizophrenia. Heliyon, 5, 7, July 2019, e02033 https://doi.org/10.1016/j.heliyon.2019.e02033 https://www.sciencedirect.com/science/article/pii/S2405844019356932?via%3Dihub

66. Loonen, A.J.M., Wilffert, B., Ivanova, S.A. (2019). Putative role of pharmacogenetics to elucidate the mechanism of tardive dyskinesia in schizophrenia. Pharmacogenomics, 20(17), 1199-1223. https://doi.org/10.2217/pgs-2019-0100 https://www.futuremedicine.com/doi/10.2217/pgs-2019-0100

67. Aftanas, L.I., Anisimenko, M.S., Berdyugina, D.A., Garanin, A.Yu., Maximov, V.N., Voevoda, M.I., Vyalova, N.M., Bokhan, N.A., Ivanova, S.A., Danilenko, K.V., Kovalenko, S.P. (2018). SIRT1 allele frequencies in depressed patients of European descent in Russia. Front. Genet, 9, 686. doi: 10.3389/fgene.2018.00686. https://www.frontiersin.org/articles/10.3389/fgene.2018.00686/full

68. Fattakhov, N., Smirnova, L., Atochin, D., Parshukova, D., Skuratovskaia, D., Painter, Q., Zatolokin, P., Semke, A., Litvinova, L., Ivanova, S. (2018). Haplotype analysis of endothelial nitric oxide synthase (NOS3) genetic variants and metabolic syndrome in healthy subjects and schizophrenia patients. International Journal of Obesity, 42, 2036-2046 https://doi.org/10.1038/s41366-018-0124-z   https://www.nature.com/articles/s41366-018-0124-z

69. Ermakov, E.A., Ivanova, S.A., Buneva, V.N., Nevinsky, G.A. (2018). Hydrolysis by catalytic IgGs of microRNA specific for patients with schizophrenia. IUBMB Life, Feb, 70(2), 153-164. doi: 10.1002/iub.1712  https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/iub.1712

70. Loonen, A.J., Ivanova, S.A. (2018). The evolutionary old forebrain as site of action to develop new psychotropic drugs. J Psychopharmacol, Sep 26, 269881118798617. doi: 10.1177/0269881118798617. https://journals.sagepub.com/doi/full/10.1177/0269881118798617

71. Ivanova, S.A., Dröge, M.J., van Vliet, B.J., Bokhan, N.A., Bosker, F.J., Loonen, A.J.M. (2018). Remaining need for in vitro test to elucidate 5-HT2C receptor functioning. Journal of Clinical Psychopharmacology, Jun 14. doi: 10.1097/JCP.0000000000000914.  https://kopernio.com/viewer?doi=10.1097%2Fjcp.0000000000000914&token=.eJyLNjQ3NTaxNNBRMjTQMzSwNNfPSi7QM0AGloYmSrEAskgIng.Mfg2sqAGkstPQDhofhnCb2BoPjs

72. Toshchakova, V.A., Bakhtiari, Y., Kulikov, A.V., Gusev, S.I., Trofimova, M.V., Fedorenko, O.Yu., Mikhalitskaya, E.V., Popova, N.K., Bokhan, N.A., Hovens, J.E., Loonen, A.J.M., Wilffert, B., Ivanova, S.A. (2017). Association of polymorphisms of 5HTTLPR and 5-HT2C genes with criminal behavior in Russian criminal offenders. Neuropsychobiology, 75(4), 200-210. doi: 10.1159/000487484. Epub 2018 Apr 5. https://www.karger.com/Article/FullText/487484

73. Levchenko, A., Losenkov, I.S., Vyalova, N.M., Simutkin, G.G., Bokhan, N.A., Wilffert, B., Loonen, A.J., Ivanova, S.A. (2018). The functional variant rs334558 of GSK3B is associated with remission in patients with depressive disorders. Pharmacogenomics & Personalized Medicine, Jul 20, 11, 121-126. doi: 10.2147/PGPM.S171423. (Scopus Q1 2019)   eCollection 2018. https://www.dovepress.com/the-functional-variant-rs334558-of-gsk3b-is-associated-with-remission--peer-reviewed-article-PGPM

74. Loonen AJM, Ivanova SA. . Circuits regulating pleasure and happiness: evolution and role in mental disorders. Acta Neuropsychiatr. 2018 Feb;30(1):29-42. doi: 10.1017/neu.2017.8. (IF 1.938)  https://www.ncbi.nlm.nih.gov/pubmed/28473012

75. Ermakov EA, Ivanova SA, Buneva VN, Nevinsky GA. Hydrolysis by catalytic IgGs of microRNA specific for patients with schizophrenia. IUBMB Life. 2018 Feb;70(2):153-164. doi: 10.1002/iub.1712    https://www.ncbi.nlm.nih.gov/pubmed/29341394

76. Loonen A.J., Ivanova S.A. Commentary on "A non-reward attractor theory of depression": A proposal to include the habenula connection. Neurosci Biobehav Rev. 2017 Feb 21. pii: S0149-7634(16)30557-7. doi: 10.1016/j.neubiorev.2017.02.007              https://www.ncbi.nlm.nih.gov/pubmed/28232092

77. Ivanova, S. A., Osmanova, D. Z., Freidin, M. B., Fedorenko, O. Y., Boiko, A. S., Pozhidaev, I. V., Semke, A. V., Bokhan, N. A., Agarkov, A. A., Wilffert, B., Loonen A. J. Identification of 5-hydroxytryptamine receptor gene polymorphisms modulating hyperprolactinemia in antipsychotic drug-treated schizophrenic patients // World J. Biol. Psychiatry.– 2017 Apr;18(3):239-246. DOI: 10.1080/15622975.2016.1224926

78. Ivanova SA, Osmanova DZ, Boiko AS, Pozhidaev IV, Freidin MB, Fedorenko OY, Semke AV, Bokhan NA, Kornetova EG, Rakhmazova LD, Wilffert B, Loonen AJ. Prolactin gene polymorphism (-1149 G/T) is associated with hyperprolactinemia in patients with schizophrenia treated with antipsychotics. Schizophr Res. 2017 Apr;182:110-114. doi: 10.1016/j.schres.2016.10.029 https://www.ncbi.nlm.nih.gov/pubmed/27776952

79. Albert Batalla, Judith R. Homberg, Tatiana V. Lipina, Guillaume Sescousse, Maartje Luijten, Svetlana A. Ivanova, Arnt F.A. Schellekens, Anton J.M. Loonen , The role of the habenula in the transition from reward to misery in substance use and mood disorders Neuroscience & Biobehavioral Reviews Available online 30 May 2017 Volume 80, September 2017, Pages 276–285 https://doi.org/10.1016/j.neubiorev.2017.03.019  https://www.ncbi.nlm.nih.gov/pubmed/28576510

80.  Geers LM, Cohen D, Wehkamp LM, van Hateren K, Koster RA, Fedorenko OY, Semke AV, Bokhan N, Ivanova SA, Kosterink JGW, Loonen AJM, Touw DJ. Dried Blood Spot Analysis for Therapeutic Drug Monitoring of Clozapine. J Clin Psychiatry. 2017 Oct 24. pii: 16m11164. doi: 10.4088/JCP.16m11164. http://www.psychiatrist.com/JCP/article/Pages/2017/v78n09/16m11164.aspx

81. Loonen AJM, Ivanova SA. Evolution of circuits regulating pleasure and happiness with the habenula in control. CNS Spectr. 2017 Nov 1:1-6. doi: 10.1017/S1092852917000748. https://www.ncbi.nlm.nih.gov/pubmed/29091022

82. Ermakov EA, Smirnova LP, Bokhan NA, Semke AV, Ivanova SA, Buneva VN, Nevinsky GA. Catalase activity of IgG antibodies from the sera of healthy donors and patients with schizophrenia. PLoS One. 2017 Sep 25;12(9):e0183867. doi: 10.1371/journal.pone.0183867. eCollection 2017 https://www.ncbi.nlm.nih.gov/pubmed/28945759

83. Loonen AJM, Kupka RW and Ivanova SA (2017) Circuits Regulating Pleasure and Happiness in Bipolar Disorder. Front. Neural Circuits 11:35. doi: 10.3389/fncir.2017.00035 https://www.ncbi.nlm.nih.gov/pubmed/28588455

84. V. D. Prokopieva, E. G. Yarygina, N. A. Bokhan, and S. A. Ivanova Use of Carnosine for Oxidative Stress Reduction in Different Pathologies. Oxidative Medicine and Cellular Longevity, vol. 2016, Article ID 2939087, DOI:10.1155/2016/2939087 

85. I.S. Losenkov, N.M. Vyalova, G.G. Simutkin, N.A. Bokhan, S.A. Ivanova An association of AKT1 gene polymorphism with antidepressant treatment response. The World Journal of Biological Psychiatry 2016 Volume 17, Issue 3, pages 239-242 http://dx.doi.org/10.3109/15622975.2015.1112921

86. Loonen AJM, Ivanova SA (2016) Circuits Regulating Pleasure and Happiness—Mechanisms of Depression. Front. Hum. Neurosci. 10:571. doi: 10.3389/fnhum.2016.00571 https://www.ncbi.nlm.nih.gov/pubmed/27891086

87. Loonen AJ, Ivanova SA. Circuits regulating pleasure and happiness: the evolution of reward-seeking and misery-fleeing behavioral mechanisms in vertebrates.  Front Neurosci. 2015 Oct 23;9:394. eCollection 2015. http://dx.doi.org/10.3389/fnins.2015.00394

88. Ermakov EA, Smirnova LP, Parkhomenko TA, Dmitrenok PS, Krotenko NM, Fattakhov NS, Bokhan NA, Semke AV, Ivanova SA, Buneva VN, Nevinsky GA. DNA-hydrolysing activity of IgG antibodies from the sera of patients with schizophrenia. Open Biol. 2015 Sep;5(9):150064. DOI: 10.1098/rsob.150064

89. Ivanova SA, Toshchakova VA, Filipenko ML, Fedorenko OY, Boyarko EG, Boiko AS, Semke AV, Bokhan NA, Aftanas LI, Loonen AJ. Cytochrome P450 1A2 co-determines neuroleptic load and may diminish tardive dyskinesia by increased inducibility. World J Biol Psychiatry. 2015 Apr;16(3):200-5. http://dx.doi.org/10.3109/15622975.2014.995222  

90. Fedorenko O.Y, Loonen A.J.M., Lang F., Toshchakova V.A., Boyarko E.G., Semke A.V., Bokhan N.A., Govorin N.V., Aftanas L.I., Ivanova S.A. Association study indicates a protective role of phosphatidylinositol-4-phosphate-5-kinase against tardive dyskinesia. Int J Neuropsychopharmacol. 2015. 18 (6) p.1-6:             DOI: http://dx.doi.org/10.1093/ijnp/pyu098

91. Ivanova SA, Loonen AJ, Bakker PR, Freidin MB, Ter Woerds NJ, Al Hadithy AF, Semke AV, Fedorenko OY, Brouwers JR, Bokhan NA, van Os J, van Harten PN, Wilffert B. Likelihood of mechanistic roles for dopaminergic, serotonergic and glutamatergic receptors in tardive dyskinesia: A comparison of genetic variants in two independent patient populations. SAGE Open Med. 2016 Apr 11;4:2050312116643673. doi: 10.1177/2050312116643673. http://journals.sagepub.com/doi/pdf/10.1177/2050312116643673

92. Loonen AJ, Ivanova SA. Circuits regulating pleasure and happiness in major depression. Med Hypotheses. 2016 Feb;87:14-21. DOI: 10.1016/j.mehy.2015.12.013

93. Svetlana A. Ivanova, Anton J. M. Loonen  Levodopa-Induced Dyskinesia Is Related to Indirect Pathway Medium Spiny Neuron Excitotoxicity: A Hypothesis Based on an Unexpected Finding, Parkinson’s Disease, vol. 2016, Article ID 6461907, 5 pages, 2016. doi:10.1155/2016/6461907. (IF 2,010). https://www.ncbi.nlm.nih.gov/pubmed/27144051

94. Ivanova S.A., Geers L.M., Al Hadithy A.F., Pechlivanoglou P., Semke A.V., Vyalova N.M., Rudikov E.V., Fedorenko O.Y., Wilffert B., Bokhan N.A., Brouwers J.R., Loonen A.J. Dehydroepiandrosterone sulphate as a putative protective factor against tardive dyskinesia. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2014 Apr 3; 50: 172-7. DOI: 10.1016/j.pnpbp.2013.12.015

95.  Anton J. M. Loonen, Svetlana A. Ivanova New insights into the mechanism of drug-induced dyskinesia. CNS Spectrums  2013  Volume 18   Issue 01  pp 15-20  DOI: http://dx.doi.org/10.1017/S1092852912000752

96. Ivanova S.A., Al Hadithy A.F., Brazovskaya N., Semke A., Wilffert B., Fedorenko O., Brouwers J.R., Loonen A.J. No involvement of the adenosine A2A receptor in tardive dyskinesia in Russian psychiatric inpatients from Siberia. Hum Psychopharmacol. 2012. V. 27. N. 3. P. 334—337. DOI: 10.1002/hup.2226

97. Ivanova S. A., Loonen A. J. M., Pechlivanoglou P., Freidin M. B., Al Hadithy A. F. Y, Rudikov E. V., Zhukova I. A., Govorin N. V., Sorokina V. A., Fedorenko O., Alifirova V. M., Semke A. V., Brouwers J. R. B. J., Wilffert B. NMDA receptor genotypes associated with the vulnerability to develop dyskinesia. Transl Psychiatry. 2012 Jan 10;2:e67  DOI: 10.1038/tp.2011.66 http://www.nature.com/tp/journal/v2/n1/full/tp201166a.html

98. Al Hadithy A. F. Y., Ivanova S. A., Pechlivanoglou P., Semke A., Fedorenko O., Kornetova E., Ryadovaya L., Brouwers J. R. B. J., Loonen A. J. M. Missense polymorphisms in three oxidative-stress enzymes (GSTP1, SOD2, and GPX1) and dyskinesias in Russian psychiatric inpatients from Siberia. Hum. Psychopharmacol. Clin. ExP. 2010. V. 25. N. 1. P. 84—91 DOI: 10.1002/hup.1087

99. Hadithy A.F.Y. Al, Ivanova S.A., Pechlivanoglou P., Semke A., Fedorenko O., Kornetova E., Ryadovaya L., Brouwers J.R.B.J., Wilffert B., Bruggeman R., Loonen A.J.M. Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia// Progress in Neuro-Psychopharmacology & Biological Psychiatry.- 2009.- N.33.- P. 475–481.  DOI: 10.1016/j.pnpbp.2009.01.010

100. Fedorenko O., Tang C.,  Sopjani M., Föller M., Gehring E.-M.,  Strutz-Seebohm N., Ureche O.N., Ivanova S., Semke A., Lang F., Seebohm G., Lang U.E. PIP5K2A-dependent regulation of excitatory amino acid transporter EAAT3 // Psychopharmacology.- 2009.- V.206.- N3- P429-435. DOI: 10.1007/s00213-009-1621-5