Personalities

Ivan Vyacheslavovich is the author and co-author of more than 100 publications in the central and regional press (including abstracts and conference materials), of which 11 articles in the journals of the HAP list, more than 35 in Web of Science and Scopus, one textbook, 4 certificates of state registration of databases, one technology and a computer program registration certificate.

Pozhidaev I.V. became the winner of the competition for the Presidential Scholarship (2018-2020) (PS-2492.2018.4) for young scientists and graduate students carrying out promising research and development in priority areas of modernization of the Russian economy on the topic “Drug-induced dyskinesias and polymorphisms of pharmacokinetic genes in schizophrenia and Parkinson's disease."

Pozhidaev I.V. took part in the following projects:

1. Russian Science Foundation grant no. 17–75–10055, 2017–2019 “Pharmacogenetics of tardive dyskinesia in schizophrenia: the role of muscarinic, adrenergic, and glutamate receptor gene polymorphisms.” Investigator
2. Russian Science Foundation grant no. 19–75–10012, 2019–2021 “New approaches to the pharmacogenetics of the metabolic syndrome in schizophrenia.” Investigator
3. RSF grant no. 21–15–00212, 2021–2023 “The role of DNA methylation and polymorphism of the glutamatergic system genes in the clinic, cognitive deficits and therapy of schizophrenia.” Principal Investigator
4. Integration project, 2018-2020 "Integrated approach for the creation of a new generation of antipsychotics" of the integrated program of the Siberian Branch of the Russian Academy of Sciences II.1. Block "Clinical and molecular genetic studies of STEP, D2R, GSK3B and DISC1 in schizophrenia". Investigator
5. RFBR no. 17–29–02205, 2017–2019 “Development of a molecular genetic panel of depressive disorders based on polymorphisms of genes for neuronal kinases, neurotrophic proteins and genes for the serotonergic system.” Investigator
6. RFBR no. 17-29-06035, 2017-2019 "New approaches to the pharmacogenetics of antipsychotic-induced hyperprolactinemia in patients with schizophrenia". Investigator
7. RFBR no. 18-315-20019, 2018-2019 "New approaches to the genetics of clinical polymorphism and neurocognitive deficit in schizophrenia". Investigator
Key Papers
1. Pozhidaev I.V., Paderina D.Z., Fedorenko O.Yu., Boiko A.S., Kornetova E.G., Bokhan N.A., Ivanova S.A. Association studies of polymorphic variants of adrenergic receptor genes and tardive dyskinesia in schizophrenia // Medical genetics. 2021. Vol. 20. No. 3 (224). pp. 36-40 (in Russian).
2. Geers LM, Pozhidaev IV, Ivanova SA, Freidin MB, Schmidt AF, Cohen D, Boiko AS, Paderina DZ, Fedorenko OY, Semke AV, Bokhan NA, Wilffert B, Kosterink JGW, Touw DJ, Loonen AJM. Association between eight P-glycoprotein (MDR1/ABCB1) gene polymorphisms and antipsychotic drug-induced hyperprolactinemia. // Br J Clin Pharmacol. 2020 Mar 21. doi: 10.1111/bcp.14288
3. Pozhidaev IV, Paderina DZ, Fedorenko OY, Kornetova EG, Semke AV, Loonen AJM, Bokhan NA, Wilffert B and Ivanova SA (2020) 5-Hydroxytryptamine Receptors and Tardive Dyskinesia in Schizophrenia. Front. Mol. Neurosci. 13:63. doi: 10.3389/fnmol.2020.00063
4. Ivan V. Pozhidaev, Anastasiia S. Boiko, Anton J.M. Loonen, Diana Z. Paderina, Olga Yu. Fedorenko, Gennadiy Tenin, Elena G. Kornetova, Arkadiy V. Semke, Nikolay A. Bokhan, Bob Wilffert, Svetlana A. Ivanova "Association of Cholinergic Muscarinic M4 Receptor Gene Polymorphism with Schizophrenia" // The Application of Clinical Genetics 22 April 2020 Volume 2020:13 Pages 97—105 https://doi.org/10.2147/TACG.S247174
5. Taichi Ochi, Natalia M. Vyalova, Innokentiy S. Losenkov, Diana Z. Paderina, Ivan V. Pozhidaev, Anton J. Loonen, German G. Simutkin, Nikolay A. Bokhan, Svetlana A. Ivanova, Bob Wilffert. Limited associations between 5-HT receptor gene polymorphisms and treatment response in antidepressant treatment-free patients with depression// Front. Pharmacol. 10:1462. doi: 10.3389/fphar.2019.01462
6. Boiko AS, Pozhidaev IV, Paderina DZ, Bocharova AV, Mednova IA, Fedorenko OY, Kornetova EG, Loonen AJM, Semke AV, Bokhan NA, Ivanova SA. Search for Possible Associations of FTO Gene Polymorphic Variants with Metabolic Syndrome, Obesity and Body Mass Index in Schizophrenia Patients. Pharmgenomics Pers Med. 2021;14:1123-1131 https://doi.org/10.2147/PGPM.S327353
7. Anastasia Levchenko, Natalia M. Vyalova, Timur Nurgaliev, Ivan V. Pozhidaev, German G. Simutkin, Nikolay A. Bokhan, Svetlana A. Ivanova NRG1, PIP4K2A, and HTR2C contain possible genetic biomarkers of several clinical subphenotypes of depression and bipolar disorder // Front. Genet. 2020, 11:936 doi: 10.3389/fgene.2020.0093
8. D.Z. Osmanova, M.B. Freidin, O.Yu. Fedorenko, I.V. Pozhidaev, A.S. Boiko, N. M. Vyalova, V.V. Tiguntsev, E.G. Kornetova, A.J.M. Loonen, A.V. Semke, B. Wilffert, N.A. Bokhan, S.A. Ivanova A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia BMC Medical Genetics 2019 20 (Suppl 1) :47 https://doi.org/10.1186/s12881-019-0773-3
9. S.A. Ivanova, D.Z. Osmanova, A.S. Boiko, I.V. Pozhidaev, M.B. Freidin, O.Yu. Fedorenko, A.V. Semke, N.A. Bokhan, E.G. Kornetova, L.D. Rakhmazova, B. Wilffert, A.J.M. Loonen Prolactin gene polymorphism (−1149 G/T) is associated with hyperprolactinemia in patients with schizophrenia treated with antipsychotics / S.A. Ivanova [et al.] // Schizophrenia Research. – 2017. – Vol. 182. – P. 110–114. (WOS:000401134500017) (DOI: 10.1016/j.schres.2016.10.029)
10. S.A. Ivanova, D.Z. Osmanova, M.B. Freidin, O.Yu. Fedorenko, A.S. Boiko, I.V. Pozhidaev, A.V. Semke, N.A. Bokhan, A.A. Agarkov, B. Wilffert, A.J.M. Loonen Identification of 5-hydroxytryptamine receptor gene polymorphisms modulating hyperprolactinaemia in antipsychotic drug-treated patients with schizophrenia / S.A. Ivanova [et al.] // World Journal of Biological Psychiatry. – 2017. – Р.239–246. (WOS:000395575700005) (DOI: 10.1080/15622975.20161224926)