Poltavskaya Evgenia
Poltavskaya Evgenia G., Ph.D., researcher at the Mental Health Research Institute of the Tomsk National Research Medical Center.
Brief Biography
Evgenia Grigoryevna graduated from the Faculty of Medicine and Biology of the Siberian State Medical University in 2013 with a degree in Medical Biophysics. Since September 2013 she has been working in the Laboratory of Molecular Genetics and Biochemistry. Evgenia Grigorievna defended her Ph.D. thesis in the specialties "Psychiatry" and "Genetics".
Research Interests
At present, the research work of Poltavskaya E.G. is carried out in the field of psychiatry and narcology, including studies of genetic mechanisms in the pathogenesis of schizophrenia, alcoholism and substance dependence.
Achievements, Awards, Grants
- Winner of the competition for young scientists at the School of Young Scientists and Mental Health Specialists "Psychiatry Yesterday, Today, Tomorrow" (Kostroma, 2014);
- Winner of the young scientists competition at the XII All-Russian School of Young Psychiatrists "Suzdal-2015" (Suzdal, 2015);
- Winner of the young scientists competition at the III All-Russian Kostroma School of Young Scientists and Mental Health Professionals (Kostroma, 2016);
- Winner of the young scientists competition at the XIII All-Russian School of Young Psychiatrists "Suzdal-2017" (Suzdal, 2017).
- Winner of the young scientists competition at the V All-Russian Kostroma School of Young Scientists and Mental Health Professionals (Kostroma, 2022);
- Member of the youth section of the Russian National Consortium for Psychiatric Genetics;
- Member of the Council of Young Scientists of the Russian Society of Psychiatrists
Poltavskaya E.G. took part in the implementation of work on grant projects:
1. RSF grant no. 19-75-10012 "New approaches to the pharmacogenetics of the metabolic syndrome in schizophrenia" (2019-2022)
2. RFBR grant no. 17-29-06035 "New approaches to the pharmacogenetics of antipsychotic-induced hyperprolactinemia in patients with schizophrenia" (2017-2019)
3. RFBR grant no. 18-315-20019 "New approaches to the genetics of clinical polymorphism and neurocognitive deficit in schizophrenia" (2018-2019)
4. Grant of the Russian Humanitarian Foundation no. 17-36-01113 "Pathophysiological parameters of nociception due to genetic characteristics as a predictor of the risk of developing substance dependence in adolescents and youth" (2017-2019)
5. Grant of the Russian Humanitarian Foundation no. 14-06-00531a “Psychosocial, ethnocultural and genetic determinants of alcohol addiction among representatives of the indigenous population of Siberia” (2014-2016)
6. RSF grant no. 14-35-00023 "Laboratory for pharmacogenetic studies of personalized therapy for mental and neurodegenerative disorders" (2014-2016)
7. RSF grant no. 14-15-00183 "Cytokine-mediated mechanisms of nociception and pathological olfaction in assessing the risk of predisposition to substance addiction" (2014-2016).
8. Federal Target Program grant no. 12-04-33072 “Pathogenesis of movement disorders in patients with endogenous mental disorders during antipsychotic therapy: the role of pharmacogenetic factors” (2012–2014).
9. Federal Target Program grant “Development of a complex of markers of major socially significant mental disorders based on the study of molecular genetic mechanisms of dysregulation of neuronal protein kinase signaling pathways” (application number in the computerized information system “2012-1.2.1-12-000-1014-008”).
10. RFBR grant no. 14-34-50916 “Study of the role of DPP6 gene polymorphism in the development of antipsychotic-induced tardive dyskinesia in patients with schizophrenia” (2014).
11. RFBR grant no. 11-04-01102-a “Studying the association of PIP5K2A kinase gene polymorphism with socially significant mental and behavioral disorders” (2011–2013).
12. State Contract no. 8140 (2012-2013).
Key Papers
1. Poltavskaya E.G., Fedorenko O.Yu., Kornetova E.G., Loonen A.J.M., Kornetov A.N., Bokhan N.A., Ivanova S.A. Study of Early Onset Schizophrenia: Associations of GRIN2A and GRIN2B Polymorphisms // Life (Basel). – 2021. –№11 (10). – P. 997. (Web of Science), doi: 10.3390/life11100997
2. Poltavskaya E.G., Fedorenko O.Y., Vyalova N.M., Kornetova E.G., Bokhan N.A., Loonen AJM, Ivanova S.A. Genetic polymorphisms of PIP5K2A and course of schizophrenia // BMC Medical Genetics. – 2020. – Vol. 21. – № Suppl 1. – P. S2. (Web of Science), doi.org/10.1186/s12881-020-01107-w
3. Poltavskaya E.G., Savochkina D.N. Analysis of the association of the PRDM12 gene with pain sensitivity in individuals with dependence on psychoactive substances. Neurology, Neuropsychiatry, Psychosomatics. - 2020 - No. 1(12) - P. 27-32. (Scopus), doi.org/10.14412/2074-2711-2020-1-27-32 (in Russian).
4. Poltavskaya E.G. The place of evidence-based medicine in the diagnosis of mental disorders // Neurological Bulletin. - 2020. - T. 52. - No. 1. - S. 82-85. (RSCI, HAP), doi.org/10.17816/nb16463 (in Russian).
5. Poltavskaya E.G., Fedorenko O.Yu. Types of the course of schizophrenia and polymorphisms of neuronal protein kinase genes on the PIP5K2A, GSK3B and AKT1 models. V.M. Bekhterev Review of Psychiatry and Medical Psychology. - 2019. - No. 4-1 - P.98-100 (RSCI, HAP), doi.org/10.31363/2313-7053-2019-4-1-98-100 (in Russian).
6. Poltavskaya E.G., Savochkina D.N. The study of polymorphism of the catechol-o-methyltransferase gene in persons with substance dependence. Omsk Psychiatric Journal. - 2019. - No. 4 (22). – C.4-6. (RSCI), doi.org/10.24411/2412-8805-2019-10401 (in Russian).
7. Poltavskaya E.G., Fedorenko O.Yu., Kornetova E.G. Association between rs1057293 polymorphism of SGK1 gene and antipsychotic-induced side effects // Omsk Psychiatric Journal. – 2018. – №3(17). – С.8-13. (РИНЦ) http://omskoop.ru/opj/2018_03.pdf (in Russian).
8. Poltavskaya E.G., Boyko A.S. Study of the association of rs10828317 and rs8341 of the PIP5K2A gene with the development of hyperprolactinemia in patients with schizophrenia on antipsychotic therapy. Pharmacogenetics and Pharmacogenomics. - 2018. - No. 2. - P.28-29. (RSCI), doi.org/10.24411/2588-0527-2018-10012 (in Russian).
9. Poltavskaya E.G., Savochkina D.N. Association of the polymorphic variant rs 6746030 of the SCN9A gene with pain sensitivity in individuals with addictive disorders. Siberian Herald of Psychiatry and Addiction Psychiatry. - 2017. - No. 4 (97) - P. 5-9. (RSCI, HAP), doi.org/10.26617/1810-3111-2017-4(97)-5-9 (in Russian).