Personalities

Kornetova Elena G.

MD, lead researcher of Endogenous Disorders Department of Mental Health Research Institute of Tomsk NRMC.

Contacts

e-mail: kornetova@sibmail.com 
tel.: +7 (3822) 73-87-75

Vita

She graduated from the Faculty of Medicine of the Tomsk Medical Institute (1996) with a degree in General Medicine, and completed residency training with a degree in Psychiatry (1996-1998) at the Mental Health Research Institute of the Siberian Branch of the Russian Academy of Medical Sciences (currently the Mental Health Research Institute of the Tomsk NRMC, Tomsk).

In 2001, she defended her thesis for the degree of Candidate of Medical Sciences: “Clinical-constitutional features and adaptive capabilities of patients with simple schizophrenia” (scientific adviser, doctor of medical sciences, professor A.V. Semke), and in 2016 - the thesis for the degree of Doctor of Medical Sciences: "Schizophrenia with a predominance of negative disorders: clinical-constitutional patterns, adaptation, therapy."

Since 1998, she has been a Junior Researcher, since 2000 a Researcher, subsequently a Senior Researcher, and since 2016, a Lead Researcher at the Department of Endogenous Disorders.

Area of scientific and clinical interests

Schizophrenia, constitution, psychopharmacotherapy, rehabilitation, adjustment

Total number of publications is more than 140, of them 12 – in foreign press.

She develops an anthropological direction in psychiatry, has repeatedly participated as a rater and researcher in multicenter clinical trials of psychotropic drugs, has been trained at international trainings, is also a highly qualified doctor, provides advisory psychiatric and psychotherapeutic help in somatic medicine - clinics of the Siberian Medical University and consultative-diagnostic Center "Professor".

Achievements, awards. grants

Member of the Russian Society of Psychiatrists (RSP).

Gratitude of the Presidium of the Tomsk Scientific Center of the Siberian Branch of the Russian Academy of Medical Sciences for conscientious work, success in work and in honor of the Day of the Medical Worker (2011).

Certificate of honor from the Presidium of the Siberian Branch of the Russian Academy of Medical Sciences for fruitful work, for contribution to the development of medical science and the protection of the health of the population of Siberia, the Far North and the Far East (2012).

Letter of gratitude from the Administration of the city of Tomsk, Siberian Branch of the RAMS in honor of the 40th anniversary of the Siberian Branch of the RAMS (2010); Winner of the Tomsk Region Prize in the field of education and science (2010), Certificate of Honor from the Administration of Tomsk (2010), Certificate of Honor from the Administration of Tomsk Region (2015).

A letter of gratitude from the Administration of the city of Tomsk for many years of conscientious work, high professionalism for the 35th anniversary of the Mental Health Research Institute and with the Day of the Medical Worker (2016).

Targacept Inc. Winston-Salem, North Carolina, United States. TC 5619-238-CRD-003 "A double-blind, placebo-controlled, multicenter parallel-group study evaluating the efficacy, safety, and tolerability of TC-5619, used as an augmentation tool to alleviate negative symptoms and improve cognitive function in schizophrenia in outpatients." 2012-2013, performer.

RFBR 17-29-06035 ofi_m "New approaches to the pharmacogenetics of antipsychotic-induced hyperprolactinemia in patients with schizophrenia" 2017-2020, performer.

Contract No. 3855 of 07.07.2015 to carry out research “Study of the associations of gene polymorphism of transporters of neurotransmitter systems in patients with schizophrenia with side effects of antipsychotic therapy (hyperprolactinemia)”, 2015, performer.

The most important publications

Monographs

1. Kornetova E.G., Boiko A.S., Borodyuk Yu.N., Semke A.V. Tardive dyskinesia in schizophrenic patients: clinical picture and risk factors. – Tomsk: New Printing Technologies, 2014. – 106 p.
2. Smirnova L.P., Buneva V.N., Kornetova E.G. Catalytic antibodies (abzymes) in schizophrenic patients: DNA-hydrolyzing activity // Biological markers of schizophrenia: search and clinical use / N.A. Bokhan, S.A. Ivanova, eds. – Novosibirsk: Publishing House of SB RAS, 2017. – P. 47-68.

Articles in peer-reviewed journals

1. Smirnova L., Fattakhov N., Parshukova D., Buneva V., Kornetova E., Semke A., Ivanova S. Dnase and protease activity of immunoglobulins G of patients with schizophrenia // European Psychiatry. – 2013. – Vol. 28, Suppl. 1. – S. 1831. doi:10.1016/S0924-9338(13)76795-6 
2. Kornetova E.G., Semke A.V. Current issues and prospects of study of schizophrenia with leading negative symptoms // Bulletin of Siberian Medicine. – 2014. – Vol. 13, No. 1. – P. 5-13. doi: 10.20538/1682-0363-2014-1-5-13
3. Kornetova E.G., Semke A.V., Dmitrieva E.G., Borodyuk Yu.N., Boiko A.S. Clinical and social risk factors of tardive dyskinesia in patients with schizophrenia in the process of treatment with antipsychotics // Bulletin of Siberian Medicine. – 2015. – Vol. 14. – No. 1. – P. 32-39. doi: 10.20538/1682-0363-2015-1-32-39
4. Smirnova L.P., Parshukova D.A., Borodiuk Iu.N., Kornetova E.G., Tkacheva G.D., Seregin A.A., Burdovitsina T.G., Semke A.V. Lipid spectrum changes and ECG in patients with paranoid schizophrenia in the course of therapy with atypical antipsychotics // S.S. Korsakov Journal of Neurology and Psychiatry. – 2015. – Vol. 115, No. 3. – P. 49-53.
5. Mikilev F.F., Kornetova E.G., Lobacheva O.A., Kornetov A.N., Semke A.V. Psychometric evaluation of symptoms and clinical dynamics of schizophrenia in depending on constitutionally-morphological type of the patients // Bulletin of Siberian Medicine. – 2016. – Vol. 15, No. 2. – P. 58-64. doi: 10.20538/1682-0363-2016-2-58-64
6. Kornetova E.G., Mikilev F.F., Lobacheva O.A., Borodyuk Yu.N., Boiko A.S, Semke A.V. Clinical and immunological features of hyperprolactinemia in schizophrenic patients treated with risperidone // Social and Clinical Psychiatry. – 2016. – Vol. 26. – No. 1. – P. 5-11. https://www.elibrary.ru/item.asp?id=26539105
7. Kornetova E., Semke A., Kornetov A., Bokhan N. Body-build and Schizophrenia: A Clinical Context // Mental Health in Family Medicine. – 2016. – Vol. 12, №3. – P. 303-306.
8. Ivanova S.A., Osmanova D.Z., Boiko A.S., Pozhidaev I.V., Freidin M.B., Fedorenko O.Y., Semke A.V., Bokhan N.A., Kornetova E.G., Rakhmazova L.D., Wilffert B., Loonen A.J. Prolactin gene polymorphism (-1149 G/T) is associated with hyperprolactinemia in patients with schizophrenia treated with antipsychotics // Schizophrenia Research. – 2016. – Vol. 182. – P. 110-114. doi: 10.1016/j.schres.2016.10.029
9. Dmitrieva E., Kornetova E. Factors of premorbid period indicating the risk of medicated noncompliance in patients with schizophrenia // European Psychiatry. – 2017. – Vol. 41, Suppl. – P. S810. doi: 10.1016/j.eurpsy.2017.01.1568
10. Kornetova E., Semke A.V., Kornetov A.N., Dmitrieva E.G., Dubrovskaya V.V., Bokhan N.A. Morphophenotypical patterns in patients with negative symptoms in schizophrenia // European Psychiatry. – 2017. – Vol. 41, Suppl. – P. S818. doi: 10.1016/j.eurpsy.2017.01.1592
11. Kornetova E., Dubrovskaya V., Kornetov A., Lobacheva O., Ivanova S., Semke A., Andreev S. Effects of risperidone and olanzapine on indices of weight and fatty component of body composition of patients with schizophrenia // European Archives of Psychiatry and Clinical Neuroscience. – 2017. – Vol. 267, Suppl. 1. – P. S62. doi: 10.1007/s00406-017-0824-8
12. Kornetova Elena G., Lobacheva Olga A., Shakhray Elena O., Dubrovskaya Victoria V., Dmitrieva Ekaterina G., Kornetov Alexander N., Petrova Valeria N., Semke Arkady V. Dynamics of clinical-social and clinical-immunological indices of patients with schizophrenia in the process of antipsychotic therapy // Siberian Herald of Psychiatry and Addiction Psychiatry. – 2017. – No. 2. – P. 21-25. https://www.elibrary.ru/item.asp?id=29432402