Personalities

Svetlana G. Krylova

Svetlana G. Krylova, doctor of biological sciences, senior researcher of the laboratory of onсopharmacology of Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences

Contact details

e-mail: krylova5935@gmail.com
Phone: 8 (3822) 41-77-47

Brief Biography

Krylova Svetlana Gennadievna in 1986 graduated from the Faculty of biology and soil of Kuibyshev Tomsk State University on the speciality "Biology". From 1980 to 1985, she worked in the Siberian branch of the All-Union Oncological Scientific Center of Academy of Medical Science of the USSR. In 1985 was credited with an official translation in SRI of Pharmacology of Tomsk Research Center RAMS to senior laboratory assistant. In connection with the election contest in 1988, was transferred to the post of research assistant. In 1989, she defended her Phd thesis on "Anticancer properties of p-tirozola" at the dissertation Council of the 001.31.01 in SRI of Pharmacology of TNC AMN. In January 1993, as the results of attestation S.G. Krylova was transferred to a post of the scientific employee, in December 1993, the senior scientific employee of laboratory oncopharmaсology. In 2005, she defended her DPhil thesis on "Plants in Siberia and the Far East therapy ulcers stomach and duodenal ulcers (experimental study)". From November 2006 till present, S.G. Krylova works as a leading scientific employee of laboratory of oncopharmacology. She is a member of the Dissertation Council, the Approbation Committee, the Academic Council of Goldberg Research Institute of Pharmacology and Regenerative Medicine.

Research Interests

Svetlana Gennadievna has more than 200 published works. Priority research confirmed 15 patents of the Russian Federation for inventions. S.G. Krylova is a co-author of 3 monographs. Under the supervision of S.G. were protected two Phd. theses. Area of scientific interests of Krylova Svetlana Gennadievna is experimental Oncology, experimental Gastroenterology, searching for new molecules and the development on their basis new drugs with anti-inflammatory and analgesic properties.

Achievements, awards, and grants

For high achievements in the sphere of education and science, providing effective influence on development of economy and social sphere of Tomsk region, Krylova S.G. was awarded the diploma of laureate of Tomsk region (2012). For many years conscientious work and high professionalism Svetlana Gennadievna was awarded the honorary diploma of the Presidium of Siberian Branch of the RAMS (2012), received the title of honored veteran of Siberian Branch of the RAS (2018).
Krylova S.G. participated in implementation of grants of federal target program "Development of the pharmaceutical and medical industry of the Russian Federation for the period until the year 2020 and beyond" and in Government contracts with the Federal Agency of Science and innovations (2009, 2012). Nowadays she participates in realization of the thematic map 054 "Development of pharmaceuticals based on natural resources of Siberia and the far East and the study of mechanisms of their action." From 2017, Krylova S.G. is a project manager "Preclinical studies of medicinal products on the basis of hexaazisowurtzitane derivatives for the treatment of pain of different etiology», conducted within the framework of the implementation of the activities of the 2.5 "Preclinical studies of innovative medicines» Pharma 2020 Federal program (State contract from August 15, 2017 # 14. N 08.11.0179).
Krylova S.П. is an expert applications for the formation and funding of works within the framework of the federal target program "Development of the pharmaceutical and medical industry of the Russian Federation for the period until the year 2020 and further perspective".

Main Publications

1. Krylova S.G., Povet’eva T.N., Zueva E.R., Amosov E.N., Razina T.G., Rybalkina O.Yu., Lopatina K.A., Suslov N.I., Nesterova Yu.V., Afanaseva O.G., Sysolyatin S.V., Kalashnikov A.I., Malykhin V.V., Dygai A.M., Zhdanov V.V., Vorozhcov A.B., Zhukov A.S., Hexaazisowurtzitane derivatives as potential sources of new drugs/in the book: HIGH-ENERGY materials: demilitarization, ANTI-TERRORISM and CIVIL APPLICATIONS. Materials of the XII International Conference «HEMs-2016". - 2016. - pp.25-30. https://elibrary.ru/author_items.asp?authorid=142191


2. Nesterova Yu.V., Povet’eva T.N., Zibareva L.N., Suslov N.I., Zueva E.P., Aksinenko S.G., Afanas’eva O.G., Krylova S.G., Amosova E.N., Rybalkina O.Yu., Lopatina K.A. Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L. //Bulletin of Experimental Biology and Medicine (Published: Springer Science+Business Media, Inc., New York, USA). – June, 2017. – Volume 163, Issue 2. – P. 18-21. https://elibrary.ru/item.asp?id=31068324


3. Lopatina K.A., Safonova E.A., Nevskaya K.V., Stakheeva M.N., Guryev A.M, Zueva E.P., Razina T.G., Krylova S.G., Amosova E.N., Belousov M.V. The influence of polysaccharides from Acorus Calamus on expression of CD274 and CD326 by cells of lung carcinoma Lewis // Newsletter experimental biology and medicine. - 2017. - T.164., No.7. - pp. 119-122 https://elibrary.ru/item.asp?id=31050582


4. Krylova S.G., Tureckova V.F., Makarova O.G., Efimova L.A., Zueva E.P., Rybalkina O.Yu. The comparative study of antiulcer activity of Aspen bark extract dry in various medicinal Forms // Pacific medical journal. - No.2 - 2015(60).- pp.18-21. https://elibrary.ru/item.asp?id=24275083


5. S.G. Krylova, Z.K.Vymyatnina, E.P. Zueva, E.N. Amosova, T.G. Razina, and V.I. Litvinenko. Effects of Cichorium intybus L. Root Extract on Secretory Activity of the Stomach in Health and Ulcer Disease // Bulletin of Experimental Biology and Medicine. - Vol.159. - N5. - September, 2015.- pp. 638-641/ https://elibrary.ru/item.asp?id=23408256


6. Efimova l. A., Krylova S.G., Zueva E.P., Krasnozchenov E.P., Khotimchenko Y.S. The study of antihelicobacter action of non-starch polysaccharide pectate calcium in vitro // Pacific medical journal. - 2014. - No.2. - pp. 50-52. https://elibrary.ru/item.asp?id=22002290


7. Tureckova V.F. Makarova. O.G.., Krylova S.G. Gastroretentive tablets and capsules with Aspen bark extract dry. Experimental study. - Saarbrucken: Palmarium Academic Publishing, 2014. -128 p. https://elibrary.ru/item.asp?id=24904547


8. Krylova S.G., Zueva E.P., Zibareva L.I., Amosov E.N., Razina T.G. Antiulcer activity of extracts from ecdisteroidcontaining plants of Lychnis and Silene Caryophyllaceae family // Bulletin of experimental biology and medicine. - 2014. – T.158., No.8. – pp. 190-194.


9. Efimova l.A., Krylova S.G., Krasnozchenov E.P., Zueva E.P., Khotimchenko Yu.S. The study of influence of non-starched polysaccharide pectate calcium on the growth and colonization of normal and pathogenic microflora in vitro//Bulletin of experimental biology and medicine. -2011. - T.151. - No.6. – pp. 630-633. https://elibrary.ru/item.asp?id=16516777


10. Goldberg E.D, Razina T.G, Zueva E.P., Amosova E.N., Krylova S.G., Lopatina K.A. Plants of Siberia and the far East and their bioactive substances as a means of supplementary therapy of tumors // Bulletin of experimental biology and medicine. - 2008. - No.2. – pp.21-29. https://elibrary.ru/contents.asp? issueid = 1124274


11. Efimova L.A., Krylova S.G., Zueva E.P., Khotimchenko Yu.S., Razina T,G., Amosova E.N., Lopatina K.A., Fomina T.I. Antiulcer activity of non-starched polysaccharides // Bulletin of the Russian Academy of medical sciences. - 2009. - №11. - pp.35-38. https://elibrary.ru/item.asp?id=13016893


12. Krylova S.G., Konovalova O.M., Zueva E.P. Correction with bark extract and Hippophae rhamnoides bines of disturbances of hormonal-metabolic status of rats under stress // Experimental and Clinical Pharmacology. - 2000. - T.63. - N4. - p.70-73. https://elibrary.ru/item.asp?id=14952630


13. Dygai A.M., Zueva E.P., Razina T.G., Amosova E.N., Krylova K.A., Lopatina K.A., Efimova l.A., Safonova E.A., Rybalkina O.Yu. Selection System of natural compounds for use in oncology practice. Experience of Pharmacology with RAMS // Pacific medical journal. - 2010. -No.2. - pp. 10-15. http://elibrary.ru/item.asp?id=16219911


14. Zueva E.P., Razina T.G., Krylova S.G., Amosova E.N., Khotimchenko M.Yu., Lopatina K.A., Efimova L.A., Safonova E.A., Rybalkina O.Yu., Khotimchenko Yu.S. The influence of chitozans with different molecular weight on development of adenocarcinoma Erlich and effectiveness of cyclophosphamide in mice // Pacific medical journal. - 2010. - No.2. - pp. 82-84. http://elibrary.ru/item.asp?id=16219931


15. Goldberg E.D., Amosova E.N., Zueva E.P., Razina T.G., Krylova S.G., Zorikov P.S. The improving the efficiency of chemotherapy and surgical methods for the treatment of tumour effects with licorice drugs//Bulletin of experimental biology and medicine . - 2008. - T.145. - No.2. – pp. 113-217. http://elibrary.ru/item.asp?id=10336662


16. Goldberg E.D., Razin T.G., Zueva E.P., Amosova E.N., Krylova S.G., Goldberg V.E. Plants in complex therapy of tumors. - M.: RAMS Publishing house, 2008. - 232 p.


17. .Zueva E.P., Reichart D.V., Krylova S.G., Razina T.G., Amosova E.N., Udut V.V. Medicinal plants in the treatment of gastric ulcer and duodenal ulcer. - Tomsk: TGU Publishing House, 2003. - 212 p.