Personalities

Elena A. Safonova

Elena A. Safonova , Candidate of Medical Sciences, Researcher of the Oncopharmacology Laboratory of the Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk NRMC.

Contact details

e-mail: safonova_7@mail.ru
Phone: +7 (3822) 41-77-47

Brief Biography

Safonova Elena Andreevna in 2008 graduated from the Medical and Biological Faculty of the Siberian State Medical University with a degree in biophysics. In 2008 she enrolled in full-time postgraduate study at the Institute of Physics and Mathematics them. E.D. After graduating, she defended her thesis on "Plant polysaccharides as correctors for cytostatic therapy of experimental tumors." Since 2011, he has been a research assistant at the Oncopharmacology Laboratory of the Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk NRMC.

Research Interests

In the field of scientific interests E.A. Safonova is studying the possibility of using natural origin drugs and biologically active substances isolated from them in the complex therapy of tumors, determining their role in the correction mechanisms of the antitumor and toxic effects of cytostatics and in increasing the antitumor resistance of the organism.

Achievements, awards, and grants

EA Safonova is the winner of the Tomsk Region Prize in the field of education, science, health care and culture for high achievements in the field of education and science, having an effective influence on the development of the economy and social sphere of the Tomsk Region (2012).
Participated in the implementation of the federal program “Development of the pharmaceutical and medical industry of the Russian Federation for the period up to 2020 and beyond,” and the State contract with the Federal Agency for Science and Innovations of the Russian Federation (2009, 2012) as co-executor. Currently he is a participant in R & D works on the topic 054 “Development of pharmacological preparations based on the natural resources of Siberia and the Far East and the study of the mechanisms of their action”.
Safonova E.A. is a co-author of the patents: “An agent that reduces the hematotoxicity of cytostatic drugs” (No. 2397774) and “Means that increase the antitumor and antimetastatic activity of cytostatic drugs” (No. 2471496).

Main Publications

1. Safonova E.A., Razina T.G., Lopatina K.A., Fedorova E.P., Zueva E.P., Gurev A.M. Reduction of the toxic effect of paclitaxel on the blood system by water-soluble polysaccharides of the mother-and-stepmother ordinary and calamus calamus // Siberian Oncological Journal. - 2010. - № 2. T 9. - P.42-46. http://elibrary.ru/item.asp?id=14309778


2. Safonova E.A., Lopatina K.A., Razina T.G., Fedorova E.P., Pakhomova A.V., Vychuzhanina A.V., Zueva E.P., Efimova L.A. Correction of the toxic effect of paclitaxel on the blood system and the small intestine epithelium with water-soluble polysaccharides of coltsfoot, calamus swamp and Echinacea purpurea // Russian Biotherapeutic Journal. - 2010. - № 2 (9). - p. 19-23. http://elibrary.ru/item.asp?id=20185038


3. Zueva E.P., Razina T.G., Amosova E.N., Krylova S.G., Lopatina K.A., Efimova L.A., Safonova E.A., Rybalkina O.Yu., Khotimchenko M .YU. The influence of chitosans with different molecular weights on the development of Ehrlich adenocarcinoma and the effectiveness of cyclophosphamide in mice // Pacific Medical Journal.-2010. - №2. - P.82-84.http: //elibrary.ru/item.asp? Id = 16219931


4. Razina T. G., Zueva E. P., Amosova E. N., Krylova S. G., Khotimchenko M. Yu., Lopatina K. A., Efimova L. A., Safonova E. A., Rybalkina O .YU. Influence of fucoidan from sea brown alga Laminaria japonica on the development of Ehrlich adenocarcinoma and Lewis lung carcinoma and the effectiveness of cyclophosphamide in mice // Pacific Medical Journal. - 2010. - №2. - P.36-39. http://elibrary.ru/item.asp?id=16219916


5. Safonova E.A., Lopatina K.A., Vetoshkina T.V., Razina T.G., Zueva E.P., Gurev A.M. Correction of hepatotoxicity of cyclophosphamide by water-soluble polysaccharides of coltsfoot and calamus calamus // Bulletin of Siberian Medicine. - 2011. - № 1.- p. 70-75. http://elibrary.ru/item.asp?id=16383563


6. Safonova E.A., Razina T.G., Zueva E.P., Lopatina K.A., Efimova L.A., Gurev A.M., Rybalkina O.Yu., Khotimchenko Yu.S. Prospects for the use of plant polysaccharides in the treatment of malignant tumors // Experimental and Clinical Pharmacology. - 2012. - № 9. - T. 75. - p. 42-47. http://elibrary.ru/item.asp?id=22569303


7. Safonova E.A., Gurev A.M., Razina T.G., Zueva E.P., Efimova L.A., Lopatina K.A. Improving the effectiveness of chemotherapy using pharmacologically active fractions isolated from the polysaccharide complex of a calamus swamp (Acorus calamus L.) // Russian Biotherapeutic Journal. - T.11. - № 4. - 2012. - P.55-58. http://elibrary.ru/item.asp?id=18983815


8. Zibareva L.N., Zueva E.P., Razina T.G., Amosova E.N., Krylova S.G., Lopatina K.A., Rybalkina O.Y., Badulina A.A., Safonova E.A., Babushkina M.S., Filonenko E.S., Galiulina A.V. Lymphis chalcedonica L. flavonoids on the development of the cyclic phosphamide // NEW OPERATIONAL TECHNOLOGIES (NEWOT'2015): Proceedings of the 5th International Scientific Conference "New Operational Technologies", Tomsk, Russia, September 29–30, 2015, Volume number: 1688, http://dx.doi.org/10.1063/1.4936026


9. Safonova E.A., Lopatina K.A., Vychuzhanina A.V., Ermolaeva L.A., Razina T.G., Zueva E.P. Reducing the toxic effect of fluorouracil on the epithelium of the small intestine with the help of plant polysaccharides. // Bulletin of experimental biology and medicine. - 2016. - №2. - T.161. - p. 274-278. http://elibrary.ru/item.asp?id=25449132