TatianaYu. Dubskaya
TatianaYu. Dubskaya, PhD, Senior Researcher of the Laboratory of Drug Toxicology of Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center.Contact details
e-mail: tatatox@mail.ruPhone: 8 (3822) 41-83-77
Brief Biography
She graduated from the Medical and Biological Faculty of the Tomsk Medical Institute in 1988, receiving a degree in biochemistry. In 1994 she defended her thesis for the degree of Candidate of Medical Sciences on the topic "Mechanisms of the hepatotoxic effect of anticancer drugs, platinum derivatives." He has held the position of Senior Researcher in the Biochemistry Group of the Laboratory of Drug Toxicology of Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center.
Research Interests
The main scientific research T.Yu. Dubskaya associated with research in the field of experimental pharmacology, toxicology, pathophysiology and related fields in order to create new drugs and develop new experimental models of pathological conditions. Conducts research on the possibility of correcting the toxic effects of drugs.
Achievements, awards, and grants
T.Yu. Dubskaya participated in the implementation of preclinical safety studies (general toxic and mutagenic properties) of more than 20 new drugs developed at the institute. Takes part in research on grants of the Federal Target Program “Development of the pharmaceutical and medical industry of the Russian Federation for the period up to 2020 and beyond”, which are conducted on the basis of the institute.
He has Gratitude on behalf of the State Duma of the Tomsk Region for high professionalism, a great personal contribution to the development of science and health care in the Tomsk Region and in connection with the 25th anniversary of the establishment of the Institute of Pharmacology of the Siberian Branch of the Russian Academy of Medical Sciences.
Main Publications
- Toxic effect of vepesid on morphology and function of the rat liver Vetoshkina T.V., Dubskaya T.Y., Fomina T.I., Ermolaeva L.A., Goldberg V.E. Bulletin of Experimental Biology and Medicine. 2007. Т. 143. № S1. С. 21-23. http://elibrary.ru/item.asp?id=28181163
- Goldberg E.D., Dygai A.M., Zhdanov V.V., Vetoshkina T.V., Guryantseva L.A., Dubskaya T.Yu., Ermolaeva L.A., Zyuzkov G.N., Simanina E.V., Sotnikova N.V., Stavrova L.A., Udut E.V., Fomina T.I., Khrichkova T.Yu. Creating experimental models and studying their regenerative possibilities of stem cells // Bulletin of experimental biology and medicine. 2007. No. S1.Pp.13. http://elibrary.ru/item.asp?id=24483835
- Ermolaeva LA, Dubskaya T.Yu., Fomina T.I., Vetoshkina TV, Goldberg V.E. The toxic effect of the anticancer drug paclitaxel on the morphofunctional state of the rat liver // Bulletin of Experimental Biology and Medicine, №2, Volume 145, 2008, p. 225-228. http://elibrary.ru/item.asp?id=10336665
- Goldberg E.D., Dygai AM, Zhdanov V.V., Zyuzkov G.N., Ermakova N.N., Vetoshkina T.V., Fomina T.I., Ermolaeva L.A., Dubskaya T. YU. Mechanisms of the therapeutic effects of granulocyte colony-stimulating factor in experimental diabetes mellitus Cell technology in biology and medicine. 2008. No. 4. P. 230-233.http://elibrary.ru/item.asp?id=12143738
- Karpova G.V., Fomina T.I., Vetoshkina T.V., Dubskaya T.Yu. Ermolaeva L. ..A .., Churin A.A. Hepatotoxicity of anticancer drugs // 25 years of the Research Institute of Pharmacology of the Siberian Branch of the RAMS. Herald of the RAMS. - 2009. - №11, P. 17-21. http://elibrary.ru/item.asp?id=13016889
- Dygai A.M., Zhdanov V.V., Zyuzkov G.N., Stavrova L.A., Simanina E.V., Udut E.V., Khrichkova T.Yu., Miroshnichenko L.A., Vereshchagin E.I., Madonov P.G., Kinsht D.N., Fomina T.I., Vetoshkina T.V., Dubskaya T.Yu., Ermolaeva L.A. Mechanisms of hepatoprotective action of immobilized granulocyte colony-stimulating factor // Bulletin of experimental biology and medicine. 2010. T. 150. No. 10. P. 371-375. http://elibrary.ru/item.asp?id=15206271